Prototype of bio-membrane/semiconductor active device

在这项研究中，作为一个生物膜/半导体有源器件的基本运动的演示，我们进行了在任意位置的光照射相分离域的形成。为了实现图案化，特别是通过激光照射，荧光脂质组成和扩散系数进行了优化。此外，为了研究蛋白质聚集的可能性，引入了膜联蛋白V。结果，在结构域结构的相同位置处观察到由膜联蛋白V引起的荧光。这表明通过结构域控制蛋白质聚集是可能的。

In this study, as a demonstration of the basic motion of a biomembrane/semiconductor active device, we performed the formation of the phase separation domains at arbitrary positions by light irradiation. In order to achieve patterning especially by laser light irradiation, fluorescence lipid composition and diffusion coefficient were optimized. Furthermore, in order to investigate the possibility of a protein aggregation, Annexin V was introduced. As a result, the fluorescence due to the Annexin V were observed at the same positions of domain structure. It suggested that the protein aggregation control by domain control was possible.