Interaction of peripheral reflexes in cardiovascular regulation during exercise

运动过程中外周反射在心血管调节中的相互作用

• 批准号: 22680049
• 负责人: ICHINOSE Masashi
• 金额: $ 16.39万
• 依托单位: Meiji University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (A)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22680049/
• 关键词: スポーツ生理学; 循環調節; 血圧; 自律神経活動; 運動; 運動生理学; 自律神経; 末梢反射

In this study, 1) we established experimental technique to quantify the characteristics of the muscle metaboreflex during dynamic exercise in humans. In addition, 2) we found that during activation of the muscle metaboreflex, the arterial baroreflex-mediated peripheral vasoconstriction is enhanced. Such interaction of the peripheral reflexes could contribute to the cardiovascular regulation during exercise. These findings advance elucidation of mechanisms of cardiovascular regulation during exercise, and will be a significant academic base in considering the safety of exerciseand the efficacy of the exercise training in promotion of health.

在这项研究中，1）我们建立了实验技术来量化人类动态运动期间肌肉代谢反射的特征。此外，2）我们发现，在肌肉代谢反射激活期间，动脉压力感受反射介导的外周血管收缩增强。周围反射的这种相互作用可能有助于运动期间的心血管调节。这些发现促进了运动过程中心血管调节机制的阐明，并将为考虑运动安全性和运动训练促进健康的功效提供重要的学术基础。

项目成果

Muscle metaboreflex activation speeds the recovery of arterial blood pressure following acute hypotension in humans

肌肉代谢反射激活可加速人类急性低血压后动脉血压的恢复

• DOI: 10.1152/ajpheart.00833.2012
• 发表时间: 2013
• 期刊: American Journal of Physiology-Heart and Circulatory Physiology
• 影响因子: 4.8
• 作者: Masashi Ichinose;Kazuhito Watanabe、 Naoto Fujii;Narihiko Kondo and Takeshi Nishiyasu
• 通讯作者: Narihiko Kondo and Takeshi Nishiyasu

Sweating responses and the muscle metaboreflex under mildly hyperthermic conditions in sprinters and distance runners

• DOI: 10.1152/japplphysiol.00212.2011
• 发表时间: 2011-08-01
• 期刊: JOURNAL OF APPLIED PHYSIOLOGY
• 影响因子: 3.3
• 作者: Amano, Tatsuro;Ichinose, Masashi;Kondo, Narihiko
• 通讯作者: Kondo, Narihiko

Changes in arterial blood pressure elicited by severe passive heating at rest is associated with hyperthermia-induced hyperventilation in humans

• DOI: 10.1007/s00421-012-2413-x
• 发表时间: 2012-05
• 期刊: European Journal of Applied Physiology
• 影响因子: 3
• 作者: Naoto Fujii;M. Ichinose;Y. Honda;B. Tsuji;Kazuhito Watanabe;N. Kondo;T. Nishiyasu

Individual differences in the heart rate response to activation of the muscle metaboreflex in humans.

• DOI: 10.1152/ajpheart.00255.2010
• 发表时间: 2010-11
• 期刊: American journal of physiology. Heart and circulatory physiology
• 作者: Kazuhito Watanabe;M. Ichinose;Naoto Fujii;Mayumi Matsumoto;T. Nishiyasu

Spontaneous baroreflex control of heart rate during activation of the muscle metaboreflex in the forearm and calf in humans

人类前臂和小腿肌肉代谢反射激活过程中心率的自发压力反射控制

• 发表时间: 2011
• 作者: Kazuhito Watanabe;Masashi Ichinose;Naoto Fujii;Bun Tsuji;Akira Sugihara;Takehiro Niwa;Takeshi Nishiyasu
• 通讯作者: Takeshi Nishiyasu