Live-cell imaging to monitor X-chromosome reactivation and stem cell reasearch

在干细胞研究中，X染色体的再激活被认为是干细胞多能大状态的一个指标。然而，目前还没有关于这一现象的监测方法的报道。因此，我们尝试开发一种基于实时成像技术的新方法来监测这种现象。这种方法将有助于我们在分子水平上理解重编程过程。这项研究的结果将对医疗保健产生相当大的影响。

In stem cell research, reactivation of X chromosomes is recognized as an indicator of the pluripotent grand state of stem cells. However, there is no report of the monitoring method on this phenomenon. Therefore, we attempt to develop a novel method to monitor this phenomenon based on a live-imaging technique. This method would help us to understand the reprogramming process at the molecular level. The outcomes of this search will have considerable impact in medical care.