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Relation of leptin and adiponectin to subclinical atherosclerosis

Relation of leptin and adiponectin to subclinical atherosclerosis
瘦素、脂联素与亚临床动脉粥样硬化的关系
批准号:
23590823
负责人:
NAKAMURA Yasuyuki
金额:
$3.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2013

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中文摘要
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英文摘要
Mean intima-media thickness (IMT), and Agaston score were significantly greater in the higher leptin concentration groups, and were significantly lower in the higher adiponectin concentration groups. In multiple linear regression models adjusted for confounders, log-leptin and log-adiponectin did not relate to IMT. In logistic regression models adjusted for age, log-leptin was significantly directly related to CAC (Agaston score>=10), but significantly inversely related to CAC in a model adjusted for multiple confounders. Log-adiponectin did not relate to CAC.Log-leptin was significantly directly related to CAC in an age-adjusted model, but was significantly inversely related to CAC in a multivariable adjusted model. The inverse relation of leptin to CAC in multivariable analysis in this study may support clinical use of leptin in weight reduction.
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DOI: 10.1007/s00394-012-0469-3
发表时间: 2013-09
期刊: European journal of nutrition
影响因子: 5
作者: [Nakamura Y, Ueshima H, Okuda N, Murakami Y, Miura K, Kita Y, Okamura T, Okayama A, Turin TC, Choudhry SR, Rodriguez B, David Curb J, Stamler J]
通讯作者: Stamler J
DOI: --
发表时间: 2012
期刊: Nutr Metab Cardiovasc Dis
影响因子: --
作者: [116.Nakamura Y, Ueshima H, Okuda N, Miura K, Kita Y, Okamura T, Turin TC, Okayama A, Rodriguez B, Curb JD, Stamler J]
通讯作者: Stamler J
Significant Inverse Association of Serum Docosahexaenoic Acid with Coronary Artery Calcification Among Men in the General Population in Japan
日本普通人群中男性血清二十二碳六烯酸与冠状动脉钙化呈显着负相关
DOI: --
发表时间: 2013
期刊:
影响因子: --
作者: [Sekikawa A, Miura K, Nakamura Y, Ueshima H, et al]
通讯作者: et al
Relation of Serum Leptin and Adiponectin Level to Serum C-Reactive Protein of Japanese in Japan and Japanese-Americans in Hawaii : The INTERLIPID Study
日本人和夏威夷日裔美国人血清瘦素和脂联素水平与血清​​ C 反应蛋白的关系:INTERLIPID 研究
DOI: --
发表时间: 2013
期刊:
影响因子: --
作者: [Nakamura Y, Ueshima H, Okuda N, Miura K, et al]
通讯作者: et al
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