Tissue Engineering for lower urinary tract by autologous bone marrow stem cell and adispose tissue

从临床角度看，尿道括约肌重建术是膀胱重建术中预防尿失禁的重要手段。首先，我们可以培养和增殖兔股骨骨髓来源的间充质干细胞和腹部脂肪组织来源的干细胞。将培养的干细胞植入损伤的尿道括约肌，通过组织学方法（免疫组化、RT-PCR法）和功能研究发现尿道括约肌的重建。

From the clinical point of view, urethral sphincter reconstruction is important to prevent urinary incontinence in the field of bladder reconstruction. At first, we could culture and proliferate the bone-marrow-derived mesenchymal stem cells derived from the femur of rabbit and abdominal adipose tissue derived stem cells. The cultured stem cells were implanted into the injured urethral sphincter, and we could found the reconstruction of the urethral sphincter by histological methods (immunohistochemistry, RT-PCR method) and functional study.