The study of the gene distribution and the role in hard tissue formation of amelogenin

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According to the results of in situ hybridization, amelogenin gene expression was observed several non tooth related tissue such as brain, kidney, eye and bone related tissues.The amelogenin gene expression in these tissues, were a significant small amount of gene expression compared with gene expression in ameloblast of incisor. The tendency of the expression level of the amelogenin gene in the tissue they become strong in the late gestation than early fetal period has been confirmed.