The identification of molecular targets for glioblastoma using mouse model transplanted transgenic neural stem cell
The identification of molecular targets for glioblastoma using mouse model transplanted transgenic neural stem cell
利用小鼠模型移植转基因神经干细胞鉴定胶质母细胞瘤的分子靶点
批准号：
23791588
负责人：
TAMASE Akira
金额：
$2.66万
依托单位：
依托单位国家：
日本
项目类别：
Grant-in-Aid for Young Scientists (B)
财政年份：
2011
资助国家：
日本
项目状态：
已结题
起止时间：
2011 至 2012
中文摘要
翻译
我们利用移植转基因神经干细胞的小鼠脑胶质瘤模型，探索了在胶质瘤干细胞中高表达的基因。用绿色荧光蛋白(GFP)标记胶质瘤干细胞。通过微阵列数据分别获得了GFP阳性和GFP阴性细胞的基因表达谱。挑选了50个候选基因。其中，有两个基因被确定为有希望的基因。
英文摘要
We explored the genes which overexpressed in glioma stem-like cells using the mouse glioma model transplanted transgenic neural stem cells. Glioma stem-like cells were labeled by Green Fluorescent Protein (GFP). The gene expression profiles of which cells are GFP positive or are GFP negative havebeen obtained by microarray data, respectively. Fifty candidate genes were picked up. Among them, two genes have been identified as promising genes.
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会议论文
The evalution of target moleculein glioma stem-like cells
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批准号：25861262
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项目类别：Grant-in-Aid for Young Scientists (B)
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资助金额：$2.66万
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财政年份：2013
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负责人：TAMASE Akira
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依托单位：
海外基金
