Development of controlled release of vancomycin sol-gel films on titanium abutment

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Sol-gel films on titanium alloy have made with vancomycin solution. In the solution of more than 10% weight concentration vancomycin, about three weeks was confirmed in the study of controlled release drug release of the film.In the morphological analysis, the stability of the films can be acquired at a thickness of 200nm revealed.To investigate the antibacterial coating, we examined the effect on the formation of the inhibition rings by immersion in a saliva 37 ℃. Formation of inhibition rings was reduced after 14 days.