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The elucidation of the transport systems under the control of the zymogen granule membrane proteins

The elucidation of the transport systems under the control of the zymogen granule membrane proteins
阐明酶原颗粒膜蛋白控制下的运输系统
批准号:
23790808
负责人:
KAWASHIMA Rei
金额:
$2.66万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012

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中文摘要
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英文摘要
GP2 knockout (-/-) mice were utilized to clarify the mechanisms of the granule formation and exocrine secretion. Our results suggest that zymogen granule accumulation is associated with both the lysosomal dysfunction in the GP2 deficient pancreas under fasted conditions. It has been suggested thatGP2 is participated the transport systems for control of the zymogen granule membrane proteins
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Inhibition of CCR8-mediated chemotaxis and LPS-induced cytokine secretion of peritoneal macrophages by a small molecule compound
小分子化合物抑制 CCR8 介导的趋化性和 LPS 诱导的腹膜巨噬细胞细胞因子分泌
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Oshio Tomoyuki, Kawashima Rei, Kawamura Yuki, Okada Toshihiko, Haga Tatsuya, Matsukawa Akihiro, Kakuta Shigeru, Iwakura Yoichiro, Dohi Taeko]
通讯作者: Dohi Taeko
ヒト唾液ムチンに対するモノクローナル抗体の作製
抗人唾液粘蛋白​​单克隆抗体的生产
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [Naitoh I, Zen Y, Nakazawa T, Ando T, Hayashi K, Okumura F, Miyabe K, Yoshida M, Nojiri S, Kanematsu T, Ohara H, Joh T, 田中秀樹,角田修一,飯田泰広,川島麗,五艘行信,石原和彦,市川尊文,栗原誠]
通讯作者: 田中秀樹,角田修一,飯田泰広,川島麗,五艘行信,石原和彦,市川尊文,栗原誠
TWEAK/Fn14 pathway mediates IL-13-induced intestinal epithelial cell death
TWEAK/Fn14 通路介导 IL-13 诱导的肠上皮细胞死亡
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [REI KAWASHIMA, YUKI I. KAWAMURA, TOMOYUKI OSHIO, TERUKI HAGIWARA, TOSHIHIKO OKADA, KYOKO INAGAKI-OHARA, PING WU, SUZANNE SZAK, YUTAKA J. KAWAMURA, FUMIO KONISHI, OKI MIYAKE, HIDEAKI YANO, TAKAFUMI ICHIKAWA, YUKIO SAITO, LINDA C. BURKLY and TAEKO DOHI]
通讯作者: LINDA C. BURKLY and TAEKO DOHI
DOI: --
发表时间:
期刊:
影响因子: --
作者: [内藤格, 中沢貴宏, 大原弘隆, REI KAWASHIMA, Itaru Naitoh, 川島麗]
通讯作者: 川島麗
Regulation of the injury via the histamine H2 receptor pathway in the small intestine
  • 批准号:
    16K09323
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $2.83万
  • 财政年份:
    2016
  • 负责人:
    KAWASHIMA Rei
  • 依托单位:
The interaction between the pathway of TWEAK-Fn14 and IL-13 in the intestinalepithelial cell regeneration
Clarify the mechanisms of Interleukin-13 induces tissue damage with modification of cell-cell adhesion in the intestinal epithelial cells
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