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An investigation of a contribution of toll-like receptor signalinginhibitory molecules to connective tissue diseases

An investigation of a contribution of toll-like receptor signalinginhibitory molecules to connective tissue diseases
Toll样受体信号传导抑制分子对结缔组织疾病的影响的研究
批准号:
23791101
负责人:
KAWASAKI Aya
金额:
$2.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012

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中文摘要
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英文摘要
We examined whether genes encoding TLR7 and TLR9 signaling inhibitory molecules and related molecule, LILRA4, LAIR1 and IRF4 and PRDM1 are involved in the susceptibility to systemic lupus erythematosus (SLE). We detected the association of 4 SNPs in LILRA4-LAIR1. On the other hand, no evidence for association of IRF4 was observed. We also detected an association of PRDM1 with SLE with nephropathy.
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会议论文
Genetic background of antineutrophil Cytoplasmic Antibody-Associated Vasculitis in a Japanese Population : association of STAT4 with myeloperoxidase antineutrophil cytoplasmic antibody-positive vasculitis
日本人群抗中性粒细胞胞浆抗体相关性血管炎的遗传背景:STAT4 与髓过氧化物酶抗中性粒细胞胞浆抗体阳性血管炎的关联
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [Kawasaki A, et al]
通讯作者: et al
Investigation of a contribution of genes coding for paired receptors, LILR and LAIR families, to connective tissue diseases
  • 批准号:
    25461467
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $3.24万
  • 财政年份:
    2013
  • 负责人:
    KAWASAKI Aya
  • 依托单位:
A comprehensive association study of IRF family genes in genetic predisposition to connective tissue diseases.
  • 批准号:
    21790935
  • 项目类别:
    Grant-in-Aid for Young Scientists (B)
  • 资助金额:
    $2.75万
  • 财政年份:
    2009
  • 负责人:
    KAWASAKI Aya
  • 依托单位:
海外基金