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Role of podoplanin in epidermal keratinocytes and psoriatic epidermis

Role of podoplanin in epidermal keratinocytes and psoriatic epidermis
平足蛋白在表皮角质形成细胞和银屑病表皮中的作用
批准号:
23791246
负责人:
HONMA Masaru
金额:
$1.25万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012

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中文摘要
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英文摘要
Our results of epidermal keratinocytes show that podoplanin is associated with the regulatory mechanism of cell adhesion and self-renewal potency. This mechanism reflects both increased proliferating pool and increased transition into differentiation process of keratinocytes in prosiatic epidermis. In addition, we revealed the novel cell density-dependent PDPN-induction mechanism in squamous cell carcinoma cell-lines, which might play an important role in tumor progression process.
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会议论文
Rapidly progressive systemic sclerosis associated with breast carcinoma: report of a case with anti-RNA polymerase III antibody.
与乳腺癌相关的快速进展系统性硬化症:抗 RNA 聚合酶 III 抗体病例报告。
DOI: 10.1111/j.1346-8138.2011.01345.x
发表时间: 2012
期刊: J Dermatol
影响因子: 3.1
作者: [Honma M, Komatsu S, Igawa S, Murakami M, Iizuka H.]
通讯作者: Iizuka H.
Intercellular contact augments EGF receptor expression to activate STAT3 which increases podoplanin expression in order to promote squamous cell carcinoma motility
细胞间接触增强 EGF 受体表达,激活 STAT3,从而增加足足蛋白表达,从而促进鳞状细胞癌运动
DOI: --
发表时间: 2013
期刊: Cell Signal
影响因子: 4.8
作者: [Fujii M, Honma M, Takahashi H, et al]
通讯作者: et al
DOI: --
发表时间: 2013
期刊:
影响因子: --
作者: [Honma M, et al.]
通讯作者: et al.
DOI: 10.1111/1346-8138.12087
发表时间: 2013-05
期刊: The Journal of Dermatology
影响因子: --
作者: [Hidetoshi Takahashi;H. Tsuji;M. Honma;Hikaru Shibaki;Satoshi Nakamura;Y. Hashimoto;Michinari Takahashi;Katsuya Koike;A. Takei;A. Ishida‐Yamamoto;H. Iizuka]
通讯作者: Hidetoshi Takahashi;H. Tsuji;M. Honma;Hikaru Shibaki;Satoshi Nakamura;Y. Hashimoto;Michinari Takahashi;Katsuya Koike;A. Takei;A. Ishida‐Yamamoto;H. Iizuka
15
    海外基金