Identification of Lung Cancer Stem Cell Markers
Identification of Lung Cancer Stem Cell Markers
批准号:
23659664
负责人:
SUZUKI Motoshi
金额:
$2.33万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
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英文摘要
By using clinical specimens, we performed IHC analysis for the putative cancer-initiating cell markers. Among the markers, we found CD166 may be the mostuseful one. To identify novel lung cancer-initiating cell markers, we analyzed an open database, screened genes that were highly expressed in CD166-positive cells, measured expression levels of such genes in the clinical specimens, and performed shRNA-induced knocking-down experiments. We identified that a gene could be a novel lung cancer-initiating cell marker, as well as a future target for the cancer treatment.
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Hybrid liposomes affect cellular lipid constituents and caveolae structures
混合脂质体影响细胞脂质成分和细胞膜穴结构
DOI:
10.1016/j.bmcl.2011.12.093
发表时间:
2012
期刊:
Bioorg Med Chem Lett
影响因子:
2.7
作者:
[吉川 豊, 藤本重行, 安井裕之, Cao K]
通讯作者:
Cao K
A pivotal role of CerS6 on the ceramide metabolic pathways and tumor metastasis in lung cancer
CerS6对肺癌神经酰胺代谢途径和肿瘤转移的关键作用
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Motoshi Suzuki, Ke Cao, Kouji Tanaka, Seiichi Kato, Chinatsu Arima, Yasuyuki Hosono, Kiyoshi Yanagisawa, Keiko Tamiya-Koizumi, Takashi Murate, Mamoru Kyogashima and Takashi Takahashi]
通讯作者:
Mamoru Kyogashima and Takashi Takahashi
DOI:
10.1016/j.bbrc.2012.10.036
发表时间:
2012-11-09
期刊:
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
影响因子:
3.1
作者:
[HosonoA, Yasuyuki, Usukura, Jiro, Takahashi, Takashi]
通讯作者:
Takahashi, Takashi
DOI:
10.1038/emboj.2011.416
发表时间:
2012-01-18
期刊:
EMBO JOURNAL
影响因子:
11.4
作者:
[Hosono, Yasuyuki, Yamaguchi, Tomoya, Takahashi, Takashi]
通讯作者:
Takahashi, Takashi
癌細胞イラストレーテッド
癌细胞图解
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[鈴木元, 高橋隆]
通讯作者:
高橋隆
共 22 条
Targeting ceramide synthase 6-dependent metastasis-prone phenotype in lung cancer cells
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批准号:26290051
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.57万
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财政年份:2014
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负责人:SUZUKI Motoshi
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依托单位:
Identification of cancer initiating cell factors and an attempt of drug development
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批准号:26670625
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.33万
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财政年份:2014
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负责人:SUZUKI Motoshi
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依托单位:
Political Economic Analysis of Coalition Formation and Institutional Building in International Governance
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批准号:23330053
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.73万
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财政年份:2011
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负责人:SUZUKI Motoshi
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依托单位:
Isolation of genomic instability genes that are associated with malignancy
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批准号:20590309
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.0万
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财政年份:2008
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负责人:SUZUKI Motoshi
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依托单位:
Analyses of Conflict and Cooperation : Integrating Theories of International Relations with Economics
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批准号:20330033
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.98万
-
财政年份:2008
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负责人:SUZUKI Motoshi
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依托单位:
Effect of repeat instability on cancer and neurological diseases
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批准号:18590290
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.55万
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财政年份:2006
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负责人:SUZUKI Motoshi
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依托单位:
DNA replication and post replication DNA repair affect the genomic instability and cancer suppression
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批准号:16590244
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.3万
-
财政年份:2004
-
负责人:SUZUKI Motoshi
-
依托单位:
International Institutions and Policy Cooperation between Democratic and Non-Democratic States
-
批准号:15530101
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.98万
-
财政年份:2003
-
负责人:SUZUKI Motoshi
-
依托单位:
海外基金