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Neural regeneration in spinal cord injury using combination of photoreactive gelatin and a fusion protein of hepatocyte growth factor

Neural regeneration in spinal cord injury using combination of photoreactive gelatin and a fusion protein of hepatocyte growth factor
使用光反应明胶和肝细胞生长因子融合蛋白的组合进行脊髓损伤的神经再生
批准号:
23659723
负责人:
TANAKA Masato
金额:
$2.33万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012

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中文摘要
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英文摘要
The purpose of this study was to investigate the effect of new therapy for spinal cord injury using photoreactive gelatin and a fusion protein of hepatocyte growth factor (CBD-HGF). In vivo experiments, the combination therapy of photoreactive gelatin and CBD-HGF was effective for the functional disorder after spinal cord injury. It was considered CBD-HGF remained into gelatin for a long stretch of time and kept its activation. Up to this day, there are no optimal biomaterials for the unique environment of the spinal cord. This study suggests that the combination therapy of our materials has a potentiality for the therapy of spinal cord injury.
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发表时间: 2012
期刊:
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