Metabolomics and polymorphisms analysis on the gynecological diseases.

妇科疾病代谢组学及多态性分析。

• 批准号: 23659780
• 负责人: MORITA Hiroki
• 金额: $ 2.33万
• 依托单位: Kobe University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23659780/
• 关键词: メタボローム解析; 婦人科腫瘍; 遺伝子多型; 産科婦人科; 婦人科腫瘍学

The purpose of this study is to elucidate metabolomics and polymorphisms about the gynecological diseases. The identification of specific biomarker about some particular diseases could be useful not only for very early diagnosis of the malignant diseases, but for the marker of the treatment effectiveness. In this study, the specific metabolic product for the marker about gynecological diseases could not be obtained. I keep on analysing the data that can be got throughout this period. I presented the findings about the disease treatment obtained during this analysis.

本研究旨在阐明妇科疾病的代谢组学和基因多态性。某些特定疾病的特异性生物标志物的识别不仅有助于恶性疾病的早期诊断，而且可以作为治疗效果的标志。在本研究中，无法获得妇科疾病标志物的特异性代谢产物。我一直在分析这段时间内可以获得的数据。我介绍了在这项分析中获得的关于疾病治疗的发现。

项目成果

Acute urinary retention caused by endometrial carcinoma withlarge cystic cervix

子宫内膜癌伴宫颈巨大囊性病变致急性尿潴留

• DOI: 10.1007/s00404-010-1635-6
• 发表时间: 2011
• 期刊: Arch Gynecol Obstet
• 影响因子: 2.6
• 作者: Takeuchi K;Tsujino T;Yabuta M;Morita H.
• 通讯作者: Morita H.

今日の治療指針 常位胎盤早期剥離

今日治疗指南：胎盘早剥

• 发表时间: 2012
• 作者: Murakami A;Yakabe K;Yoshidomi K;Sueoka K;Nawata S;Yokoyama Y;Tsuchida S;Fahd Al-Mulla;Sugino N;森田宏紀
• 通讯作者: 森田宏紀

Successful medical treatment with octreotide for chyloperitoneum following paraaortic lymphadenectomy in the treatment of gynecologic malignancies: a report of 2 cases.

奥曲肽成功治疗妇科恶性肿瘤主动脉旁淋巴结切除术后乳糜腹膜2例报告。

• 发表时间: 2012
• 期刊: J Reprod Med.
• 作者: Fujiwara H;Sato Y;Ideta A;Aoyagi Y;Araki Y and Imakawa K;吉川裕之;Morita H ( Takeuchi K)
• 通讯作者: Morita H ( Takeuchi K)

化学療法抵抗性・再発卵巣癌に対するリポゾーマル化ドキソルビシン（ PLD）を用いたSalvage chemotherapyの検討

使用脂质体阿霉素（PLD）对化疗耐药/复发性卵巢癌进行挽救性化疗检查

• 发表时间: 2012
• 作者: Makihara N;Yamasaki M;Morita H;Yamada H;松本光司;森田宏紀,蝦名康彦,新谷 潔,宮原 義也,中林 幸士,山田 秀人;森田宏紀
• 通讯作者: 森田宏紀

Successful medical treatment with octreotide for chyloperitoneum following paraaortic lymphadenectomy in the treatment of gynecologic malignancies: a report of 2 cases

奥曲肽治疗妇科恶性肿瘤主动脉旁淋巴结清扫术后乳糜腹膜成功2例报告

• 发表时间: 2011
• 期刊: J Reprod Med
• 影响因子: 0.2
• 作者: Takeuchi K;Fujiwara K;Tsujino T;Morita H
• 通讯作者: Morita H