Understanding the nitrogen assimilation by the mathematical model in Bacillus subtilis
Understanding the nitrogen assimilation by the mathematical model in Bacillus subtilis
批准号:
24780072
负责人:
TAKAHASHI Hiroki
金额:
$2.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2012
资助国家:
日本
项目状态:
已结题
起止时间:
2012-04-01 至 2014-03-31
中文摘要
对添加氮源后枯草芽孢杆菌WT和MGB874菌株的生长速率进行了监测。结果表明,WT与MGB874对氮的响应无显著差异。并对sigA进行了GeF-Seq分析。仅在MGB874菌株中就发现了13个sigA隐藏位点。有趣的是,sigA结合在glnR的上部区域,这表明谷氨酸在MGB874中的积累会受到sigA谱变化的影响。
英文摘要
We performed the monitoring of the growth rate of Bacillus subtilis WT and MGB874 strains after adding the nitrogen source. As the results, there were not significant difference between the responses to nitrogen in WT and those in MGB874. Moreover, GeF-Seq analysis for sigA was conducted. We revealed 13 sigA biding sites only in MGB874 strain. Interestingly, sigA was bound to the upper region of glnR, suggesting that the accumulation of glutamic acid in MGB874 would be affected by alternation of sigA profile.
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DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Takahashi H, Oshima T, Clayton SR, Hobman JL, Tobe T, Kanaya S, Ogasawara N, Stekel DJ.]
通讯作者:
Stekel DJ.
数理モデルに触れてみよう
让我们尝试一下数学模型
DOI:
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发表时间:
2013
期刊:
日本生物工学会.生物工学会誌
影响因子:
--
作者:
[Manabe K, Kageyama Y, Morimoto T, Shimizu E, Takahashi H, Kanaya S, Ara K, Ozaki K, Ogasawara N., Aiyada Aroonsri, 高橋弘喜]
通讯作者:
高橋弘喜
[論文発表]
[论文介绍]
DOI:
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发表时间:
期刊:
影响因子:
--
作者:
[]
通讯作者:
DOI:
10.1093/dnares/dst008
发表时间:
2013-06
期刊:
DNA research : an international journal for rapid publication of reports on genes and genomes
影响因子:
--
作者:
[Ueda T, Takahashi H, Uyar E, Ishikawa S, Ogasawara N, Oshima T]
通讯作者:
Oshima T
数理モデルアプローチによる大腸菌の亜鉛制御機構の解明
使用数学模型方法阐明大肠杆菌中的锌调节机制
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[高橋弘喜,大島拓, Clayton Selina R, Hobman Jon L,戸邉亨,金谷重彦,小笠原直毅, Stekel Dov J.]
通讯作者:
Stekel Dov J.
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