In toto understanding of organ function by integrated analysis of multicellular networks mediated by intercellular delivery of metabolites
In toto understanding of organ function by integrated analysis of multicellular networks mediated by intercellular delivery of metabolites
批准号:
17H06270
负责人:
ITOH Hiroshi
金额:
$16.64万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Research (Pioneering)
财政年份:
2017
资助国家:
日本
项目状态:
已结题
起止时间:
2017-06-30 至 2020-03-31
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Novel treatment of chronic kidney disease through regulation of adenylate metabolism
通过调节腺苷酸代谢治疗慢性肾脏病
DOI:
--
发表时间:
2017
期刊:
影响因子:
--
作者:
[宮下 和季, 藤井 健太郎, 伊藤 裕]
通讯作者:
伊藤 裕
A semi-quantitative mass imaging technique revealed region-specific alteration of adenylates in the murine kidney after transient ischemia and reno-protective effect of febuxostat by ameliorating ATP levels in the cortex.
半定量质量成像技术揭示了短暂性缺血后小鼠肾脏中腺苷酸的区域特异性变化,以及非布索坦通过改善皮质中 ATP 水平的肾保护作用。
DOI:
--
发表时间:
2018
期刊:
影响因子:
--
作者:
[藤井健太郎, 宮下和季, 久保亜紀子, 佐藤正明, 萩原あいか, 井上博之, 竜崎正毅, 末松誠, 伊藤裕]
通讯作者:
伊藤裕
腎皮髄境界アデノシンによる虚血腎保護効果の検討
皮质髓质缘腺苷对缺血性肾脏保护作用的考察
DOI:
--
发表时间:
2017
期刊:
影响因子:
--
作者:
[4.藤井 健太郎, 宮下 和季, 久保 亜紀子, 佐藤 正明, 萩原 あいか, 井上 博之, 竜崎 正毅, 末松 誠, 伊藤 裕]
通讯作者:
伊藤 裕
腎皮髄境界アデノシン集積の虚血腎における保護的役割の可視化解析
皮质髓质腺苷积累对缺血肾脏的保护作用的可视化分析
DOI:
--
发表时间:
2017
期刊:
影响因子:
--
作者:
[11.藤井 健太郎, 宮下 和季, 久保 亜紀子, 佐藤 正明, 萩原 あいか, 井上 博之, 竜崎 正毅, 末松 誠, 伊藤 裕]
通讯作者:
伊藤 裕
Febuxostat exerted reno-protective effects after transient ischemia by promoting ATP recovery in the cortex: visualization of renal adenine nucleotides by an imaging mass-spectrometry technique
非布索坦通过促进皮质中 ATP 恢复在短暂性缺血后发挥肾保护作用:通过成像质谱技术观察肾腺嘌呤核苷酸
DOI:
--
发表时间:
2018
期刊:
影响因子:
--
作者:
[K. Miyashita, K. Fujii, A. Kubo, M. Sato, A. Hagiwara, H. Inoue, M. Suematsu, H. Itoh]
通讯作者:
H. Itoh
共 23 条
Spiral progression of DNA damage repair, epigenetic alterations and metabolic changes in metabolic kidney diseases
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批准号:20H00535
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项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$29.2万
-
财政年份:2020
-
负责人:ITOH Hiroshi
-
依托单位:
Development of novel therapies using neutrophil functions mediated by the autophagy machinery against multi-drug resistant bacterial infections
-
批准号:26670484
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项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.25万
-
财政年份:2014
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负责人:ITOH Hiroshi
-
依托单位:
Influence of mechanical stress applied to ES/iPS cells on organelle control and cell metabolism/differentiation
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批准号:24659454
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.41万
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财政年份:2012
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负责人:ITOH Hiroshi
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依托单位:
Analysis of the novel family of G protein-coupled receptor
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批准号:21370056
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.06万
-
财政年份:2009
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负责人:ITOH Hiroshi
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依托单位:
Regulation of cell-metabolism by cardiovascular hormones and the comprehensive application to metabolic syndrome.
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批准号:21390286
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.48万
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财政年份:2009
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负责人:ITOH Hiroshi
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依托单位:
Transcriptionaland translational regulation of peptide factors for the growth and differentiation of gastrointestinal epithelial cells
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批准号:20590382
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.0万
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财政年份:2008
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负责人:ITOH Hiroshi
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依托单位:
Cardiovascular-endocrinological approach for elucidation of the molecular mechanism of "Metabo-aging"
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批准号:19390255
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.15万
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财政年份:2007
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负责人:ITOH Hiroshi
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依托单位:
Pathophysiological mechanisms of peptides involved in the proliferation and differentiation of gastrointestinal mucosal epithelial cells.
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批准号:17590354
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2005
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负责人:ITOH Hiroshi
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依托单位:
Identification and analysis of new molecules that regulate G protein signaling
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批准号:17079006
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$50.69万
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财政年份:2005
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负责人:ITOH Hiroshi
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依托单位:
Functional analysis of regulatory mechanism of G protein signal network
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批准号:17370051
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.22万
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财政年份:2005
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负责人:ITOH Hiroshi
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依托单位:
Elucidation of significance of derangement of cell differentiation in metabolic syndrome ("cell mapping) and development of cell re-differentiation therapy using human ES cells
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批准号:17390270
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.92万
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财政年份:2005
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负责人:ITOH Hiroshi
-
依托单位:
Therapeutic mechanism of vitamin B12 on sleep wake-rhythm disorders
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批准号:16591165
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.05万
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财政年份:2004
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负责人:ITOH Hiroshi
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依托单位:
Study of characteristic role of lower lying energy levels in optical relaxation processes
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批准号:15540316
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.11万
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财政年份:2003
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负责人:ITOH Hiroshi
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依托单位:
Study on function and molecular mechanism of G protein signal network
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批准号:15370057
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.6万
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财政年份:2003
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负责人:ITOH Hiroshi
-
依托单位:
Application of human ES-derived vascular progenitor cells to elucidation of vascular development/differentiation and vascular regeneration medicine
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批准号:15209028
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$29.12万
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财政年份:2003
-
负责人:ITOH Hiroshi
-
依托单位:
Functional analysis of a novel nuclear peptide H2RSP and its roles in the regeneration of injured gastrointestinal mucosa
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批准号:15590351
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.18万
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财政年份:2003
-
负责人:ITOH Hiroshi
-
依托单位:
Influence of antioxidant capacity on arterial compliance
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批准号:14580028
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.98万
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财政年份:2002
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负责人:ITOH Hiroshi
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依托单位:
Roles of bioactive peptides (growth factors) in the regeneration of injured gastrointestinal mucosa
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批准号:13670223
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.98万
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财政年份:2001
-
负责人:ITOH Hiroshi
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依托单位:
Significance of vascular hormones in vasculoangiogenesis and vascular endocrinological approach to organ protection and regeneration
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批准号:13470218
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$6.85万
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财政年份:2001
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负责人:ITOH Hiroshi
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依托单位:
Identification of vascular progenitor cells from monkey ES cells and application for cell implantation therapy with search for novel vascular inducing factor
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批准号:13557064
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$6.34万
-
财政年份:2001
-
负责人:ITOH Hiroshi
-
依托单位:
海外基金