Spiral progression of DNA damage repair, epigenetic alterations and metabolic changes in metabolic kidney diseases
Spiral progression of DNA damage repair, epigenetic alterations and metabolic changes in metabolic kidney diseases
批准号:
20H00535
负责人:
ITOH Hiroshi
金额:
$29.2万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (A)
财政年份:
2020
资助国家:
日本
项目状态:
已结题
起止时间:
2020-04-01 至 2023-03-31
中文摘要
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英文摘要
期刊论文(37)
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DOI:
10.1007/s00125-021-05467-7
发表时间:
2021-08
期刊:
Diabetologia
影响因子:
8.2
作者:
[Sasaki H, Saisho Y, Inaishi J, Watanabe Y, Tsuchiya T, Makio M, Sato M, Nishikawa M, Kitago M, Yamada T, Itoh H]
通讯作者:
Itoh H
DNA-damaged podocyte-CD8 T cell crosstalk exacerbates kidney injury by altering DNA methylation
DNA 损伤的足细胞-CD8 T 细胞串扰通过改变 DNA 甲基化加剧肾损伤
DOI:
10.1016/j.celrep.2023.112427
发表时间:
2023
期刊:
Cell Reports
影响因子:
8.8
作者:
[Nakamichi Ran, Hishikawa Akihito, Chikuma Shunsuke, Yoshimura Akihiko, Sasaki Takashi, Hashiguchi Akinori, Abe Takaya, Tokuhara Tomoko, Yoshimoto Norifumi, Nishimura Erina Sugita, Hama Eriko Yoshida, Azegami Tatsuhiko, Nakayama Takashin, Hayashi Kaori, Itoh Hiroshi]
通讯作者:
Itoh Hiroshi
DOI:
10.1016/j.ekir.2022.01.006
发表时间:
2022-04
期刊:
KIDNEY INTERNATIONAL REPORTS
影响因子:
6
作者:
[Adachi, Keika, Uchiyama, Kiyotaka, Muraoka, Kaori, Nakayama, Takashin, Yasuda, Marie, Miyashita, Kazutoshi, Tokuyama, Hirobumi, Wakino, Shu, Itoh, Hiroshi]
通讯作者:
Itoh, Hiroshi
DOI:
10.1007/s00125-020-05349-4
发表时间:
2021-01-05
期刊:
DIABETOLOGIA
影响因子:
8.2
作者:
[Amiya, Takeru, Nakamoto, Nobuhiro, Kanai, Takanori]
通讯作者:
Kanai, Takanori
“Endocrine Supremacism” of new version in the Anthropocene
人类世新版本的“内分泌至上主义”
DOI:
10.1507/endocrj.ej20221130
发表时间:
2023
期刊:
Endocrine Journal
影响因子:
2
作者:
[Iwata Kentaro, Mikami Yohei, Kato Motohiko, Yahagi Naohisa, Kanai Takanori, Watanabe M. Nakamura Y. Sato S. Niino M. Fukaura H. Tanaka M. Ochi H. et al, Itoh Hiroshi]
通讯作者:
Itoh Hiroshi
共 19 条
In toto understanding of organ function by integrated analysis of multicellular networks mediated by intercellular delivery of metabolites
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批准号:17H06270
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项目类别:Grant-in-Aid for Challenging Research (Pioneering)
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资助金额:$16.64万
-
财政年份:2017
-
负责人:ITOH Hiroshi
-
依托单位:
Development of novel therapies using neutrophil functions mediated by the autophagy machinery against multi-drug resistant bacterial infections
-
批准号:26670484
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.25万
-
财政年份:2014
-
负责人:ITOH Hiroshi
-
依托单位:
Influence of mechanical stress applied to ES/iPS cells on organelle control and cell metabolism/differentiation
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批准号:24659454
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项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.41万
-
财政年份:2012
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负责人:ITOH Hiroshi
-
依托单位:
Analysis of the novel family of G protein-coupled receptor
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批准号:21370056
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$12.06万
-
财政年份:2009
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负责人:ITOH Hiroshi
-
依托单位:
Regulation of cell-metabolism by cardiovascular hormones and the comprehensive application to metabolic syndrome.
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批准号:21390286
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.48万
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财政年份:2009
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负责人:ITOH Hiroshi
-
依托单位:
Transcriptionaland translational regulation of peptide factors for the growth and differentiation of gastrointestinal epithelial cells
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批准号:20590382
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.0万
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财政年份:2008
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负责人:ITOH Hiroshi
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依托单位:
Cardiovascular-endocrinological approach for elucidation of the molecular mechanism of "Metabo-aging"
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批准号:19390255
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.15万
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财政年份:2007
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负责人:ITOH Hiroshi
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依托单位:
Pathophysiological mechanisms of peptides involved in the proliferation and differentiation of gastrointestinal mucosal epithelial cells.
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批准号:17590354
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2005
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负责人:ITOH Hiroshi
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依托单位:
Identification and analysis of new molecules that regulate G protein signaling
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批准号:17079006
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$50.69万
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财政年份:2005
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负责人:ITOH Hiroshi
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依托单位:
Functional analysis of regulatory mechanism of G protein signal network
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批准号:17370051
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.22万
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财政年份:2005
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负责人:ITOH Hiroshi
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依托单位:
Elucidation of significance of derangement of cell differentiation in metabolic syndrome ("cell mapping) and development of cell re-differentiation therapy using human ES cells
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批准号:17390270
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.92万
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财政年份:2005
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负责人:ITOH Hiroshi
-
依托单位:
Therapeutic mechanism of vitamin B12 on sleep wake-rhythm disorders
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批准号:16591165
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.05万
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财政年份:2004
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负责人:ITOH Hiroshi
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依托单位:
Study of characteristic role of lower lying energy levels in optical relaxation processes
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批准号:15540316
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.11万
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财政年份:2003
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负责人:ITOH Hiroshi
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依托单位:
Application of human ES-derived vascular progenitor cells to elucidation of vascular development/differentiation and vascular regeneration medicine
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批准号:15209028
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$29.12万
-
财政年份:2003
-
负责人:ITOH Hiroshi
-
依托单位:
Study on function and molecular mechanism of G protein signal network
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批准号:15370057
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.6万
-
财政年份:2003
-
负责人:ITOH Hiroshi
-
依托单位:
Functional analysis of a novel nuclear peptide H2RSP and its roles in the regeneration of injured gastrointestinal mucosa
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批准号:15590351
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.18万
-
财政年份:2003
-
负责人:ITOH Hiroshi
-
依托单位:
Influence of antioxidant capacity on arterial compliance
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批准号:14580028
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.98万
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财政年份:2002
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负责人:ITOH Hiroshi
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依托单位:
Roles of bioactive peptides (growth factors) in the regeneration of injured gastrointestinal mucosa
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批准号:13670223
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.98万
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财政年份:2001
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负责人:ITOH Hiroshi
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依托单位:
Significance of vascular hormones in vasculoangiogenesis and vascular endocrinological approach to organ protection and regeneration
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批准号:13470218
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$6.85万
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财政年份:2001
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负责人:ITOH Hiroshi
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依托单位:
Identification of vascular progenitor cells from monkey ES cells and application for cell implantation therapy with search for novel vascular inducing factor
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批准号:13557064
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$6.34万
-
财政年份:2001
-
负责人:ITOH Hiroshi
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依托单位:
海外基金