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Transcriptionaland translational regulation of peptide factors for the growth and differentiation of gastrointestinal epithelial cells

Transcriptionaland translational regulation of peptide factors for the growth and differentiation of gastrointestinal epithelial cells
肽因子的转录和翻译调节对胃肠道上皮细胞生长和分化的影响
批准号:
20590382
负责人:
ITOH Hiroshi
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

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中文摘要
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英文摘要
MicroRNA (miRNA) expression pattern and target mRNAs of squamous cell carcinoma (SCC) are different from those of other organ's malignancies. MiR-205 might be a specific marker miRNA of both normal and malignant squamous epithelia, while miR-21 might be a putative oncogenic miRNA in SCC. In addition, several miRNAs including miR-200c and miR-27b are down-regulated by HGF stimulation. These miRNAs might play an important role for the translation of HGF downstream functional molecules.
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会议论文
Expression of microRNAs in squamous cell carcinoma of human head and neck(HNSCC)and the esophagus(ESCC)and their regulation by hepatocyte growth factor
microRNA在人头颈鳞状细胞癌(HNSCC)和食管癌(ESCC)中的表达及其肝细胞生长因子的调控
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Kimura S, Naganuma S, Susuki D, Hirono Y, Yamaguchi A, Fujieda S, Sano K, Itoh H]
通讯作者: Itoh H
頭頚部扁平上皮癌細胞株におけるHGF によるマイクロRNA 発現調節
HGF对头颈鳞状细胞癌细胞系中microRNA表达的调控
DOI: --
发表时间: 2008
期刊:
影响因子: --
作者: [鈴木弟, 長沼誠二, 木村相泰, 喜多村直実, 藤枝重治, 伊藤浩史]
通讯作者: 伊藤浩史
Expression of microRNAs in squamous cell carcinoma of human head and neck (HNSCC))and the esophagus (ESCC)
microRNA在人头颈鳞状细胞癌(HNSCC)和食管癌(ESCC)中的表达
DOI: --
发表时间: 2010
期刊: miR-205 and miR-21are specific markers for HNSCC and ESCC、Oncol.Rep. 23
影响因子: --
作者: [Kimura S, Naganuma S, Susuki D, Hirono Y, Yamaguchi A, Fujieda S, Sano K, Itoh H]
通讯作者: Itoh H
HGF刺激による大腸癌細胞株の形態変化に関与するmiRNAの発現変動
HGF刺激诱导的结直肠癌细胞系形态变化中miRNA表达的变化
DOI: --
发表时间: 2008
期刊:
影响因子: --
作者: [長沼誠二, 鈴木弟, 木村相泰, 喜多村直実, 伊藤浩史]
通讯作者: 伊藤浩史
26
    Spiral progression of DNA damage repair, epigenetic alterations and metabolic changes in metabolic kidney diseases
    • 批准号:
      20H00535
    • 项目类别:
      Grant-in-Aid for Scientific Research (A)
    • 资助金额:
      $29.2万
    • 财政年份:
      2020
    • 负责人:
      ITOH Hiroshi
    • 依托单位:
    In toto understanding of organ function by integrated analysis of multicellular networks mediated by intercellular delivery of metabolites
    • 批准号:
      17H06270
    • 项目类别:
      Grant-in-Aid for Challenging Research (Pioneering)
    • 资助金额:
      $16.64万
    • 财政年份:
      2017
    • 负责人:
      ITOH Hiroshi
    • 依托单位:
    Development of novel therapies using neutrophil functions mediated by the autophagy machinery against multi-drug resistant bacterial infections
    • 批准号:
      26670484
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.25万
    • 财政年份:
      2014
    • 负责人:
      ITOH Hiroshi
    • 依托单位:
    Influence of mechanical stress applied to ES/iPS cells on organelle control and cell metabolism/differentiation
    • 批准号:
      24659454
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.41万
    • 财政年份:
      2012
    • 负责人:
      ITOH Hiroshi
    • 依托单位:
    海外基金