New imaging technologies and assessment of regeneration patterns for the optimization of computer-assisted planning and risk analysis for living donor liver transplantation

新的成像技术和再生模式评估，用于优化活体肝移植的计算机辅助规划和风险分析

• 批准号: 56685592
• 负责人: Professor Dr. Massimo Malagó
• 金额: --
• 依托单位: Institut für Diagnostische und Interventionelle Radiologie und Neuroradiologie
• 依托单位国家: 德国
• 项目类别: Clinical Research Units
• 财政年份: 2007
• 资助国家: 德国
• 起止时间: 2006-12-31 至 2014-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/56685592?language=en
• 关键词: New; imaging; technologies; assessment; regeneration

The goal of the project is the optimization of preoperative planning for living donor liver transplantations and the exploration of regeneration patterns after transplantation. Based on the findings of the ongoing project and new imaging technologies, main focuses of the project are: (1) the assessment of regeneration regarding morphology, angiogenesis, revascularization of intrahepatic vascular systems and the growth of liver and territorial volume, (2) the development of a model for advanced risk analysis including the prediction of revascularization for the hepatic veins, (3) the investigation of new imaging modalities and contrast media, and (4) the development of new planning tools for state-of-the-art and new image data including the automation of methods for the evaluation of potential donors and the optimization of algorithms for extraction of bile ducts and hepatic arteries.

该项目的目标是优化活体肝移植的术前计划并探索移植后的再生模式。基于正在进行的项目和新的成像技术的研究结果，该项目的主要重点是：（1）评估肝内血管系统的形态、血管生成、血运重建以及肝脏和领土体积的再生，（2）开发高级风险分析模型，包括预测肝静脉血运重建，（3）研究新的成像模式和造影剂， (4) 为最先进的新图像数据开发新的规划工具，包括潜在捐赠者评估方法的自动化以及胆管和肝动脉提取算法的优化。