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Establishment of Early Detection For Infantile Hearing Loss Using Distortion product otoacoustic emissions (DPOAEs)

Establishment of Early Detection For Infantile Hearing Loss Using Distortion product otoacoustic emissions (DPOAEs)
利用失真产物耳声发射 (DPOAE) 建立婴儿听力损失的早期检测
批准号:
09670852
负责人:
YASUHARA Akihiro
金额:
$1.73万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
1997
资助国家:
日本
项目状态:
已结题
起止时间:
1997 至 1998

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中文摘要
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英文摘要
This study compares the clinical usefulness of distortion product otoacoustic emissions (DPOAEs) with the auditory brainstem response (ABR) for children (from neonates in the neonatal intensive care unit to adolescents) for the evaluation of hearing impairment.Subjects were 36 neonates (67 ears), 43 children (62 ears) and 10 adults (20 ears). Both DPOAEs and ABR were performed on the same day. DPOAEs were recorded using the Scout (Bio-logic Co.). We defined neonates as having normal hearing when the thresholds of wave V of ABR were* 45 dB HL (*35 dB in children and adults). (1) We decided DP gram - noise floor (NF) with DPOAE.In adults we obtained DPOAEs in all frequencies, but could not obtain DPOAEs at f2=977 Hz in neonates and f2=537, 684 Hz in children with normal hearing because of high noise floors. DPOAE recording time was 36 minutes shorter than that of ABR ; (2) We defined as normal DPOAEs, the number of frequencies which showed the DPgram-noise floor*4 dB was *four at six f2 frequencies, from 1, 416 Hz to 7, 959 Hz ; (3) Normal thresholds of ABR and normal DPOAEs showed the same percentages, i.e. 68.7%, but the percentage of different results between ABR and DPOAIEs was 6.0%. DPOAEs were not obtained in children with otitis media with effusion regardless normal ABR.Our study indicates that DPOAIEs represent a simple procedure, which can be easily performed in the NICU to obtain reliable results in high risk neonates. Results obtained by DPOAIEs were comparable to those obtained by the more complex procedure of ABR.DPOAE can be useful for detecting of hearing impairments.
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A Ochi, A Yasuhara et al: "Comparison of DPOAE with ABR for clinical use in neonatal intensive care unit. Recent Advances in Human Neurophysiology" I.Hashimoto & R.Kakigi, Elsevier Science, 8 (1998)
A Ochi、A Yasuhara 等人:“DPOAE 与 ABR 在新生儿重症监护室临床应用的比较。人类神经生理学的最新进展” I.Hashimoto
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安原昭博: "小児における磁気刺激運動誘発電位:発達的変化と中枢運動神経系の可塑性の証明" 臨床脳波. 39. 94-98 (1997)
Akihiro Yasuhara:“儿童磁刺激运动诱发电位:中枢运动神经系统发育变化和可塑性的证据”临床脑电图 39. 94-98 (1997)。
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22
    Maturation of central motor nervous system and development of its impairment
    • 批准号:
      06670841
    • 项目类别:
      Grant-in-Aid for General Scientific Research (C)
    • 资助金额:
      $1.15万
    • 财政年份:
      1994
    • 负责人:
      YASUHARA Akihiro
    • 依托单位:
    海外基金