Development of Amperometric Biochemical Imaging Sensors Using Photoconductive Materials

在本研究中，进一步发展了化学成像传感器系统，以实现更高的性能和多功能，以满足未来应用的要求。以动态变化的电化学系统为例，进行了可视化和定量分析。实现了pH以外的化学量的可视化。提出了一种高速测量系统。首先，通过测量电解后电极附近离子浓度的分布，观察离子的扩散过程。根据菲克定律，观察到离子浓度的高斯分布。实验确定了不同离子的离子扩散常数。其次，开发了一种具有Au点阵列图案的传感器，用于可视化氧化还原电位分布。作为应用，测量了卟啉的光响应。最后，提出了一种用于化学成像传感器的高速测量系统。本研究开发的技术可以结合应用于各种标本的化学成像。

In this study, the chemical imaging sensor system was further developed to achieve higher performance and multifunctions that will meet the requirements of future applications. As an example, a dynamically changing electrochemical system was visualized and quantitatively analyzed. Visualization of chemical quantities other than pH was realized. A high-speed measurement system was proposed.Firstly, the diffusion process of ions was observed by measuring the distribution of ion concentrations in the proximity of the electrode after electrolysis. The Gaussian distribution of the ion concentration was observed as derived from the Fick's law. The ionic diffusion constants were experimentally determined for various ions. Secoedly, a sensor with a Au dot array pattern was developed for visualization of the redox potential distribution. As an application, the photo response of the porphirin was measured. Finally, a high-speed measurement system was proposed for the chemical imaging sensor.The technologies developed in this study can be combined and applied to chemical imaging of various specimens.