3D Craniofacial Growth Simulation System in Cleft Lip and Palate Patients

对早期应用上颌前牵引矫治器的唇腭裂患者进行术前预处理阶段上颌骨额部生长量的预测。选择北海道大学齿科医院口腔正畸科收治的单侧唇腭裂患者22例，男13例，女9例。治疗前22例患者的平均年龄为6岁7个月（范围为5岁7个月至8岁2个月）。所有患者均接受了上颌前牵引矫治器治疗，治疗时间均在1年以上。这些病例在1岁6个月时在同一医院的口腔外科通过推回机制修复了腭。在治疗前阶段和间隔一年拍摄的正面和侧面头颅X线片用于分析。利用头颅额位片，应用Andoh等方法， 关于我们 f测量鼻中隔。从头颅侧位片测量2个角度和4个线性头影测量。对矫治器引起的额部生长量与治疗前颅面形态进行相关性分析。并进行了多元回归分析。结果表明：（1）上颌前牵引后上颌骨额部生长量与后上面部高度及鼻中隔弯曲度的相关系数均达到显著水平。2）利用术前颅面形态数据，通过多元回归分析，建立了上颌额部生长量的预测公式; 3）根据建立的公式，可以预测上颌额部的生长量。少

The prediction of the quantity of frontal growth of the maxilla at the pretreatment stage was carried out in cleft lip and palate patients who used maxillary protraction appliance at an early period. 22 unilateral cleft lip and palate patients (13 males, 9 females) were selected from the Orthodontic Clinic of Hokkaido University Dental Hospital who already received lip and palate repair. The mean age of these 22 patients at the pretreatment stage was 6 years 7 months (Ranging between 5 years 7 months to 8 years 2 months). All these patients had undergone maxillary protraction appliance therapy with the treatment duration more than one year. The palate was repaired by push back mechanism in these cases at the age of about 1 year 6 months, in the Department of Oral Surgery of the same hospital. Frontal and lateral cephalograms taken at pretreatment stage and at an interval of one year were used for the analysis. Using the frontal cephalogram and applying the Andoh etc method, curveture o … More f the nasal septum was measured. From the lateral cephalogram 2 angular and 4 linear cephalometric measurements were measured. The correlation analysis between the amount of frontal growth caused by the appliance and the pretreatment craniofacial pattern was carried out. Further, multiple regression analysis was also done. The following results were obtained :1) The correlation coefficients between the amount of frontal growth of maxilla following the use of maxillary protraction appliance and post upper facial height and also the curveture of nasal septum presented significant results. However the results were not sufficient for prediction of the amount frontal growth of the maxilla.2) The formula for the prediction of the amount of frontal growth of the maxilla was established by multiple regression analysis using the data of the craniofacial pattern at pretreatment stage.3) It can be suggested that from the established formula, the amount of frontal growth of the upper jaw can be predicted. Less