3D Craniofacial Growth Simulation System in Cleft Lip and Palate Patients

对早期使用上颌牵引器的唇腭裂患者进行预处理阶段上颌额部生长量的预测。选取北海道大学口腔医院正畸门诊已行唇腭裂修复术的单侧唇腭裂患者22例（男13例，女9例）。22例患者在预处理阶段的平均年龄为6岁7个月（5岁7个月至8岁2个月）。所有患者均行上颌牵引器治疗，治疗时间均在1年以上。本组患儿年龄约为1岁6个月，均在同一医院口腔外科采用推回机制修复腭裂。在预处理阶段和间隔一年拍摄的额侧脑电图用于分析。采用额部脑电图和Andoh等方法测量鼻中隔的弯曲度。从侧位脑电图测量了2个角和4个直线测量。对矫治器造成的额部生长量与预处理颅面形态的相关性进行了分析。进一步进行多元回归分析。结果表明：1)上颌拔除器使用后上颌正面生长量与术后上面部高度及鼻中隔弯曲度的相关系数均有显著性差异。但结果不足以预测上颌骨额部生长的数量。2)利用预处理阶段颅面图数据，通过多元回归分析，建立上颌额部生长量的预测公式。3)根据所建立的公式，可以预测上颌额部生长量。少

The prediction of the quantity of frontal growth of the maxilla at the pretreatment stage was carried out in cleft lip and palate patients who used maxillary protraction appliance at an early period. 22 unilateral cleft lip and palate patients (13 males, 9 females) were selected from the Orthodontic Clinic of Hokkaido University Dental Hospital who already received lip and palate repair. The mean age of these 22 patients at the pretreatment stage was 6 years 7 months (Ranging between 5 years 7 months to 8 years 2 months). All these patients had undergone maxillary protraction appliance therapy with the treatment duration more than one year. The palate was repaired by push back mechanism in these cases at the age of about 1 year 6 months, in the Department of Oral Surgery of the same hospital. Frontal and lateral cephalograms taken at pretreatment stage and at an interval of one year were used for the analysis. Using the frontal cephalogram and applying the Andoh etc method, curveture o … More f the nasal septum was measured. From the lateral cephalogram 2 angular and 4 linear cephalometric measurements were measured. The correlation analysis between the amount of frontal growth caused by the appliance and the pretreatment craniofacial pattern was carried out. Further, multiple regression analysis was also done. The following results were obtained :1) The correlation coefficients between the amount of frontal growth of maxilla following the use of maxillary protraction appliance and post upper facial height and also the curveture of nasal septum presented significant results. However the results were not sufficient for prediction of the amount frontal growth of the maxilla.2) The formula for the prediction of the amount of frontal growth of the maxilla was established by multiple regression analysis using the data of the craniofacial pattern at pretreatment stage.3) It can be suggested that from the established formula, the amount of frontal growth of the upper jaw can be predicted. Less