How AIDS influences on African Endemic Kaposi's sarcoma?

我们研究了卡波西肉瘤(KS)的流行病学转变，在1980年至1997年的18年间，覆盖了肯尼亚东非西部的西部、尼扬萨和裂谷三省。人们普遍认为，自上世纪80年代中期以来，艾滋病疫情一直在该地区蔓延，S在比较艾滋病流行前后对KS的地质病理研究结果时，提出了以下看法：KS在所有恶性肿瘤中的出现频率从0.6‘/，上升到0.8’/；2.KS的男女比例从艾滋病流行前的9：1转变为6：1；3.KS在儿童早期(5岁左右)和中年组(50岁以上)的年龄分布在艾滋病流行前的两个高峰变成了三个高峰，其中包括艾滋病流行后的青春期年龄组(20-30岁)，4.KS患者的平均年龄由艾滋病流行前的40岁向流行后的36岁转变。5.艾滋病流行后成年患者中播散型和侵袭型KS的发生率升高。6.KS在艾滋病流行前极少发现的半干旱地区和热带高原地区的居民中传播迅速。这些发现表明，在肯尼亚西部艾滋病流行后，与艾滋病相关的KS数量一直在增加，并迅速蔓延。东非。

We studied an epidemiological transition of Kaposi's sarcoma (KS), covering three provinces, Western, Nyanza and Rift Valley Provinces in the western part of Kenya East Africa during the 18-year period between 1980 and 1997. It is generally accepted that AIDS epidemics has been spreading in this area since the middle of the 1980's. When comparing the results of geopathological study on KS before and after the AIDS epidemic; I . The frequency of KS among all malignant tumors has increased to 0.8'/, from 0.6'/, , 2. The male to female ratio of KS has shifted to 6:1 after AIDS epidemic from 9:1 before AIDS epidemic, 3. Two peaks of the age distribution of KS in the early childhood (around 5 years old) and the middle age group (over 50 years old) before AIDS epidemic have changed to three peaks, including the adolescent age group (20 - 30 years old) after AIDS epidemic, 4 The mean age of the KS patients has shifted to 36 years old after AIDS epidemic from 40 years old before AIDS epidemic, 5. The frequency of disseminated and aggressive form of KS with lymph node involvement among the adult patients has elevated after AIDS epidemic, 6. KS is rapidly spreading among the inhabitants in semi-arid areas and tropical highlands, where very few patients were found before AIDS epidemic. These findings suggest that AIDS-related KS has been increasing in number and spreading rapidly after AIDS epidemic in western part of Kenya. East Africa.