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Joint Study on the Development of Novel Joint Prostheses

Joint Study on the Development of Novel Joint Prostheses
新型关节假体开发联合研究
批准号:
10044165
负责人:
MURAKAMI Teruo
金额:
$2.5万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B).
财政年份:
1998
资助国家:
日本
项目状态:
已结题
起止时间:
1998 至 1999

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中文摘要
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英文摘要
The object of this research is to conduct the joint research between Kyushu University, The University of Leeds and University of Bradford to elucidate the lubrication and wear mechanism in artificial joints and develop novel joint prostheses. Members of this joint research visited Japan or United Kingdom for mutual discussion. Furthermore, during their visiting the presentations of papers on this research project were carried out at the international conferences, I.e., at the Third World Congress of Biomechanics, 25th Leeds-Lyon Symposium on Tribology, 1st Asia Int. Conf. on Tribology, Asiatrib'98, 26th Leeds-Lyon Symposium on Tribology and 12th International Symposium on Ceramics in Medicine. At the International Symposium on Lubrication Mechanism in Natural and Artificial Joints, which was organized by Prof. Murakami and Prof. Fisher at the 25th Meeting of Japanese Society of Clinical Biomechanics and Related Research, Dr. Jin and Dr. Sawae presented their papers as symposists.In th … More is joint study, the following results were shown. The fundamental mechanism in adaptive multimode lubrication in natural synovial joints was discussed by focusing the lubricating ability of cartilage surface layer. The geometric feature of knee joint was indicated by 3D Computer Graphics technique. On the lubrication mechanism in artificial joints, the fluid film formation, friction or wear in knee prosthesis models with compliant artificial cartilage such as polyurethane, silicone rubber, polyvinylalcohol (PVA) hydrogel and semi-interpenetrating polymer network (SIPN) hydrogel were evaluated by simulator or sliding tests. Atomic Force Microscopy (AFM) observation was effective in evaluation of changes in surface layer of natural articulator cartilage and artificial cartilage. The superiority in fluid film formation during walking for transverse elliptical conjunction to longitudinal one with the same contact area in knee prostheses was shown in numerical analysis. The friction and wear in existing artificial joints composed of metal or ceramics and ultra-high molecular weight polyethylene (UHMWPE), ceramics-on-ceramics, metal-on-metal were evaluated by unidirectional and multidirectional sliding tests and simulators. The influence of multi-directional motion, constituents of lubricants, material properties and geometrical design with surface roughness on wear behavior were summarized. The properties of wear particles and their biological reaction were investigated. The friction control of elastomeric material by applied electric field and wear reduction of metal-on-metal pair by magnetic field were demonstrated. Less
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会议论文
T.Murakami: "Role of Surface Layers of Natural and Artificial Cartilage in Thin Film Lubrication"Lubrication at Frontier, Elsevier. 737-747 (1999)
T.Murakami:“天然和人造软骨表面层在薄膜润滑中的作用”前沿润滑,Elsevier。
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Y.Nakanishi: "Improvement of Wear Characteristic of Metal-on-Metel Artificial Hip Joint by means of Magnetic Field"JSME International Journal.. Vol.42 No3. 552-559 (1999)
Y.Nakanishi:“通过磁场改善金属对金属人工髋关节的磨损特性”JSME 国际期刊.. Vol.42 No3。
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通讯作者:
T. Murakami: "Role of Surface Layers of Natural and Artifical Cartilage in Thin Film Lubrication"Lubrication at Frontier, Elsevier. 737-747 (1999)
T. Murakami:“天然和人造软骨表面层在薄膜润滑中的作用”前沿润滑,爱思唯尔。
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15
    Elucidation of adaptive lubrication mechanism with low friction and minimum wear in natural synovial joints and development of artificial hydrogel cartilage with super lubricity based on bionic design
    • 批准号:
      23000011
    • 项目类别:
      Grant-in-Aid for Specially Promoted Research
    • 资助金额:
      $290.28万
    • 财政年份:
      2011
    • 负责人:
      MURAKAMI Teruo
    • 依托单位:
    Development of reversing agent for multidrug resistance and new chemotherapy by utilizing genistein
    • 批准号:
      18590162
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.42万
    • 财政年份:
      2006
    • 负责人:
      MURAKAMI Teruo
    • 依托单位:
    Elucidation of Adaptive Multimode Lubrication Mechanism, Self-Organization and Restoration Mechanism in Natural Synovial Joints
    • 批准号:
      15200037
    • 项目类别:
      Grant-in-Aid for Scientific Research (A)
    • 资助金额:
      $27.37万
    • 财政年份:
      2003
    • 负责人:
      MURAKAMI Teruo
    • 依托单位:
    Micro- and Nano-Scopic Biomechanics of Articular Cartilage Focusing Chondrocytes and Surrounding Tissue
    • 批准号:
      15086212
    • 项目类别:
      Grant-in-Aid for Scientific Research on Priority Areas
    • 资助金额:
      $21.82万
    • 财政年份:
      2003
    • 负责人:
      MURAKAMI Teruo
    • 依托单位:
    海外基金