Inflammation and Pathogenesis Training Program

摘要 这一新培训计划的主要目标是培养熟练、严谨和富有创造力的科学家，这些科学家将 在炎症过程和人类发病机制之间建立新的联系。伊利诺伊大学 路易斯维尔处于有利地位，从现有的学员中挑选具有领导潜力的学员，从而产生很大的影响 生物医学科学综合方案(IPIBS)，提供有关研究课题的持续培训 微生物学和免疫学。这种跨学科的方法将把35名教职员工聚集在一起，他们都是 富有成效的科学家，具有丰富的指导经验和资金充足的研究项目，专注于i) 癌症的炎症个体发生和免疫监测，II)自身免疫性疾病的机制，III) 宿主-微生物相互作用的细胞和分子机制，iv)传染病动物模型，v) 微生物区系在调节炎症性疾病中的作用，vi)多微生物群落和 炎症，以及vii)炎症驱动的疾病及其对宿主生理的影响。参选前支持 在IPIBS中，所有学生都可以获得路易斯维尔大学资助的津贴和福利，其中包括 实验室轮换，免疫学、炎症、微生物学和发病机制方面的高级教学培训。 候选人资格前培训还包括研究生存技能，包括赠款的开发和组成， 口头陈述，科学写作和出版，专业网络，以及广泛的 负责任的研究行为。为了获得最大的点对点正面影响，每年有两名学生 他们在成功完成他们头两年的工作时表现出了非凡的表现 作为IPIBS研究员的研究生教育将从T32培训补助金中挑选出来，为期两年。 来自不同背景的学生，根据他们作为IPIBS的成就，展示出最具潜力的学生 研究生课程、资格考试和研究项目的研究员将被挑选出来，以便 培养他们作为研究科学家的学术领导技能和卓越表现。这项额外的培训将会进行 通过学生组织特定项目的讨论俱乐部，每年接待两位知名演讲者 在突出炎症和发病机制之间重要关系的学科中， 由培训导师和论文委员会对他们的研究进展进行审查。该计划将是 由两名董事监督，与指导委员会密切合作，包括对 内部和外部咨询的培训计划的组织、领导、目标和结果 委员会。

Abstract The major objective of this new training program is to produce skilled, rigorous, and creative scientists who will make novel connections between inflammatory processes and human pathogenesis. The University of Louisville is well-positioned to have high impact by selecting trainees with leadership potential from its existing Integrated Programs in Biomedical Sciences (IPIBS) for continued training on research topics that bridge microbiology and immunology. This interdisciplinary approach will bring together 35 faculty who are all highly productive scientists with extensive mentoring experience, and well-funded research programs, focused on i) inflammatory ontogeny and immune surveillance of cancer, ii) mechanisms of autoimmune disorders, iii) cellular and molecular mechanisms of host-microbial interactions, iv) animal models of infectious disease, v) the role of the microbiota in regulation of inflammatory diseases, vi) polymicrobial communities and inflammation, and vii) inflammation-driven disease and its impact on host physiology. Pre-candidacy support from IPIBS, in which all students receive stipends and benefits funded by the University of Louisville, includes laboratory rotations, advanced didactic training in immunology; inflammation; microbiology; and pathogenesis. Pre-candidacy training also includes research survival skills, including grant development and composition, oral presentations, scientific writing and publishing, professional networking, along with extensive training in the responsible conduct of research. To attain the highest positive peer-to-peer impact, each year two students who have demonstrated exceptional performance while successfully completing their first two years of graduate education as IPIBS Fellows, will be selected for two years of support from the T32 training grant. Students from diverse backgrounds who show the most potential, based on their achievements as IPIBS Fellows in graduate coursework, a qualifying exam, and in their research projects, will be selected in order to foster their academic leadership skills and excellence as research scientists. This additional training will occur through student organization of a program-specific discussion club, hosting two high profile speakers per year in disciplines that highlight important relationships between inflammation and pathogenesis and rigorous review of their research progress by a training mentor and dissertation committee. The program will be overseen by two Directors working closely with a Steering Committee, including an independent evaluation of the training program’s organization, leadership, objectives and outcomes by Internal and External Advisory Committees.