Coordination Center Component

计划摘要-先导研究 提供关键的试点资金，以支持全国初级研究人员进行的最先进的临床相关研究。 这个国家是我们“使用智能技术评估现实世界中心”的一个重要服务， 绩效（C-STAR）医疗康复资源计划。我们将使用几种方法来达到 我们的目标人群（主要是初级康复研究人员和临床医生）在全国各地的成员： (i)我们的C-STAR网站，（ii）我们的康复措施数据库-平均吸引约11，000人 每日点击的准确的个人谁可能是试点资金的候选人，和（iii）通过专业 互动-我们的PI，核心董事和关键人员将在许多 他们在全国范围内参加有关会议。我们将采取措施，确保我们的外展服务对象是来自 通过有针对性地与历史上的黑人大学进行外联， 以及其他大学的少数民族事务办公室。C-STAR试点资金的申请将 这是一个两阶段的过程。首先，我们将需要一个简单的意向书（LOI），其中包括项目名称，半- 具体目标的页面描述，研究者和关键人员的NIH风格的生物小册子，以及封面 页面，要求提供信息，使我们能够选择具有适当专业知识的审查小组（即， 工程、成果、临床、实施和社区参与），基于项目的目标， 受试者人群和研究领域（实验室内、诊所内或真实世界评估，或两种或更多种 交叉域）。如果意向书被选中，我们将需要一个完整的应用程序，一个月后，这将包括 一个额外的3页摘要的方法，预算，并从家庭机构的支持信。 意向书和完整的申请将通过我们的C-STAR门户网站提交，并通过硝基进行管理- 竞赛软件，由西北大学临床和翻译科学研究所开发。 申请将由中心核心主任和相关关键人员进行客观评估; Leora Cherney， 博士，试点研究主任，将召集审查小组，并监督审查过程。我们预计， 在研究类型、研究的患者人群和技术方面的各种资助研究 就业。我们会每年两次接受申请，并每年批出6个试点项目，每个项目的直接资助总额为 费用高达25，000美元。此外，还将提供全额机构间接费用，以确保使用试点资金 用于研究所有申请人都将收到C-STAR教师对其项目和指导的广泛反馈 如所期望或需要的。获得资助的申请人可以选择是否在家中进行研究 或在SRALab。申请人将有机会获得我们的四个核心：工程，临床，成果， 实施科学与社区参与。我们将优先考虑以下项目：（i）支持初级研究人员 具有吸引人的想法，特别是那些来自代表性不足的群体的想法，（ii）有可能推动 康复研究和受益患者，（iii）将导致校外资金和职业发展。

Project Summary—Pilot Studies Providing critical pilot funding to support state-of-the-art, clinically relevant studies by junior researchers across the country is an essential service of our “Center for use of Smart Technologies to Assess Real-world Performance (C-STAR) Medical Rehabilitation Resource program. We will use several methods to reach members of our target populations (primarily junior rehabilitation researchers and clinicians) across the country: (i) our C-STAR website, (ii) our Rehabilitation Measures Database—which attracts an average of about 11,000 daily hits from precisely the individuals who may be candidates for pilot funding, and (iii) through professional interactions—our PIs, Core Directors and key personnel will reach out to potential applicants during the many relevant meetings they attend nationwide. We will take steps to ensure that our outreach targets individuals from underrepresented populations in rehabilitation research through targeted outreach to historically black colleges and universities and to offices of minority affairs at other universities. Application for C-STAR pilot funding will be a two-stage process. First, we will require a simple Letter of Intent (LOI) that includes the project title, a half- page description of the specific aims, an NIH-style biosketch for the investigator and key personnel, and a cover page that asks for information that will allow us to select a review panel with appropriate expertise (i.e., engineering, outcomes, clinical, implementation and community engagement), based on the goals of the project, subject population, and domain of the research (in-lab, in-clinic, or real-world assessments, or two or more intersecting domains). If the LOI is selected, we will require a full application, one month later, that will consist of an additional 3-page summary of the approach, a budget, and a letter of support from the home institution. The LOI and full application will be submitted through our C-STAR portal and managed through NITRO- competitions software, developed by Northwestern University Clinical and Translation Sciences Institute. Applications will be objectively evaluated by Center Core Directors and relevant key personnel; Leora Cherney, PhD, Pilot Studies Director, will convene the review panel and oversee the review process. We anticipate a wide variety of funded studies, in terms of the study type, patient population under study, and the technologies employed. We will solicit applications twice a year and award 6 pilot projects per year, each with a total direct cost of up to $25,000. In addition, full institutional indirect costs will be provided to ensure pilot funding is used for research. All applicants will receive extensive feedback on their projects and mentorship from C-STAR faculty as desired or needed. Applicants who are funded may choose whether to conduct their research at their home institution or at SRAlab. Applicants will have access to our four cores: Engineering, Clinical, Outcomes, and Implementation Science & Community Engagement. We will prioritize projects that (i) support junior researchers with intriguing ideas, in particular, those from underrepresented groups, (ii) have the potential to advance rehabilitation research and benefit patients, and (iii) will lead to extramural funding and career advancement.