Expansion of SARS-CoV-2 Testing Supplement, Chicago Clinical Trials Unit

芝加哥临床试验中心 SARS-CoV-2 检测补充的扩展

• 批准号: 10166472
• 负责人: Babafemi O Taiwo
• 金额: $ 81.41万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-06-17 至 2022-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10166472
• 关键词: 2019-nCoV; AIDS prevention; AIDS/HIV problem; Address; Adult; Area; Award; Bacterial Drug Resistance; Chicago; Clinical; Clinical Research; Clinical Trials Unit; Communities; Community Participation; Development; HIV; Health; Hepatitis; Human Resources; Illinois; Laboratories; National Institute of Allergy and Infectious Disease; Parents; Performance; Persons; Pharmacy facility; Population Heterogeneity; Positioning Attribute; Prevention; Prevention strategy; Productivity; Research; Research Personnel; Research Priority; Resources; Risk; Scientific Advances and Accomplishments; Testing; Therapeutic; Tuberculosis; United States; Universities; Vaccines; Wellness Center; clinical research site; comorbidity; effective therapy; ethnic diversity; experience; metropolitan; prevent; programs; racial diversity; research study; treatment strategy; urban area

Parent Award Project Summary The Chicago Clinical Trials Unit (CCTU) is a consortium of five Clinical Research Sites (CRSs) which will address three priority clinical research areas of the NIAID: 1) adult HIV therapeutic strategies including HIV cure, noninfectious comorbidities, and infectious co-morbidities of hepatitis and tuberculosis; 2) vaccines to prevent HIV; and 3) integrated HIV prevention strategies. The CCTU consists of five highly experienced and scientifically productive CRSs that are uniquely positioned to develop, implement and adapt the clinical research priorities of the NIAID clinical research priority areas. The CCTU has a proven track record and will continue its productivity through active engagement with a diverse host of at risk and HIV-impacted communities, participation in high impact, ground-breaking clinical research studies, efficient management of resources and critical performance oversight of the clinical activities, laboratories, and pharmacies. The CCTU includes CRSs and personnel that have long term and productive involvement with three of the research networks; the fourth-antibacterial resistance-being a new network in this consortium. The CRSs and their network affiliations include: Northwestern University (adult HIV therapeutic strategies); University of Illinois Chicago (vaccines to prevent HIV, integrated HIV prevention), Rush University (adult HIV therapeutic strategies), University of Chicago (integrated HIV prevention strategies) and Trinity Health & Wellness Center (adult HIV therapeutic strategies). Four of the CRSs are located in Chicago, an ethnically and racially diverse urban area of 9.5 million persons that is the third largest metropolitan region in the United States and one of the major urban HIV epicenters. The aims of this proposal are: development, implementation and adaptation of the clinical research program of the 1) Adult HIV Therapeutics Strategy Network, 2) the Vaccines to Prevent HIV Network, 3) the Integrated HIV Prevention Strategies Network, and 4) Bidirectional engagement of the relevant and at risk HIV-infected/impacted communities with the CCTU clinical researchers. The CCTU is well positioned to reach diverse populations and contribute significantly to the NIAID research agenda.

家长奖项目总结 芝加哥临床试验单位（CCTU）是一个由五个临床研究中心（CRS）组成的联盟，将 解决NIAID的三个优先临床研究领域：1）成人艾滋病毒治疗策略，包括艾滋病毒 肝炎和结核病的治愈、非感染性共病和感染性共病; 2）疫苗， 预防艾滋病毒; 3）综合艾滋病毒预防战略。中央反恐组由五名经验丰富的 科学生产的CRS，具有独特的定位，以开发，实施和适应临床 NIAID临床研究优先领域的研究优先事项。中央反恐组有良好的记录， 通过积极参与各种风险和受艾滋病毒影响的人， 社区，参与高影响力，突破性的临床研究，有效管理 对临床活动、实验室和药房的资源和关键绩效进行监督。中央反恐组 包括CRS和长期参与其中三项研究的人员， 网络;第四-抗菌耐药性-是这个财团中的一个新网络。CRS及其 网络附属机构包括：西北大学（成人艾滋病毒治疗策略）;伊利诺伊大学 芝加哥（预防艾滋病毒的疫苗，艾滋病毒综合预防），拉什大学（成人艾滋病毒治疗 战略）、芝加哥大学（艾滋病毒综合预防战略）和Trinity健康与保健中心 （成人艾滋病治疗策略）。其中四个CRS位于芝加哥，这是一个种族和种族多元化的城市。 城市面积950万人，是美国第三大都市区，也是美国最大的城市之一。 主要的城市艾滋病中心。本提案的目标是：制定、执行和调整 1）成人艾滋病治疗战略网络的临床研究计划，2）预防艾滋病的疫苗 艾滋病毒网络，3）艾滋病毒综合预防战略网络，以及4）艾滋病毒 相关的和有风险的艾滋病毒感染/受影响的社区与CCTU临床研究人员。中央反恐组很好 能够接触到不同的人群，并为NIAID研究议程做出重大贡献。