Cancer Prevention and Control

癌症预防和控制计划：项目概要/摘要 癌症预防和控制（CPC）计划的中心主题是将其研究成果转化为 在实践和政策中，改善癌症的预防、检测、治疗和控制。中共 该计划致力于提高所有受癌症影响的人的生活质量，包括一个大的非洲人。 美国人口在MCC集水区内服务。MCC获得了基于少数民族的区别 NCI肿瘤学研究计划社区网站，以进一步推进这一重要领域的研究。 此外，CPC临床试验和该计划的大部分基础科学研究解决了这方面的差异。 人口中国共产党计划有36名成员，代表12个部门和4所学校。目前 CPC计划有一个总的同行评审的癌症相关的资金基础约650万美元的直接 其中近230万美元来自NCI，超过300万美元来自其他NIH研究所。2011年期间 截至2015年，CPC计划共有475种出版物，其中22%是计划内出版物，10%是计划内出版物 是跨项目的该计划的科学目标突出了其主题：（1）减少 癌症风险和（2）改善与癌症相关的护理，两者都通过以下跨领域主题联系在一起： 缓解差距。方案协调会继续在这些领域产生重大影响， 计划的成就：将MCC的基础科学发现转化为一种新型吸烟的临床试验 戒烟疗法（目前正在与匹兹堡大学癌症研究所合作进行IIa期临床试验 研究所）;告知FDA和世卫组织关于电子烟等风险降低的烟草产品的烟草政策 与CPC的第一个多PI P50补助金;通过控制高风险人群的肥胖来降低癌症风险- 青少年和非洲裔美国人;改善癌症筛查决策;提高患者和 护理人员与癌症护理的经验;确定医疗补助和其他政策对获得护理的影响; 确定非裔美国人参加临床研究试验的障碍;并制定方法， 克服这些障碍。根据国家癌症研究所促进多学科研究的优先事项，MCC促进了 通过设立一个专门用于CPC跨方案试点的奖励计划， 这些项目中有几个最近促成了大型外部资助赠款项目。价值由MCC增加 通过每月的研讨会、方案间 研究务虚会，竞争性CPC试点赠款，并通过学生和实习生奖学金的支持。在 总的来说，CPC计划是MCC内部一个重要的、动态的和不断发展的计划，它解决了独特的 MCC集水区的需求，以及更普遍的国家。该项目以其充满活力的研究 议程，参与的多学科成员，以及MCC的持续支持， 建立在其高质量的基础科学，临床，政策和成果研究的影响。

CANCER PREVENTION AND CONTROL PROGRAM: PROJECT SUMMARY/ABSTRACT The central theme of the Cancer Prevention and Control (CPC) program is to translate its research findings into practice and policy to improve the prevention, detection, treatment, and control of cancer. The CPC program strives to enhance the quality of life of all individuals affected by cancer, including a large African American population served within the MCC catchment area. MCC received distinction as a Minority Based NCI Oncology Research Program Community Site to further advance research in this important area of need. Additionally, CPC clinical trials and much of the program’s basic science research addresses disparities in this population. The CPC program has 36 members representing 12 departments and 4 schools. Currently, the CPC program has a total peer-reviewed cancer-related funding base of approximately $6.5 million in direct costs, of which nearly $2.3 million is from the NCI and over $3 million is from other NIH institutes. During 2011 to 2015, the CPC program had a total of 475 publications, of which 22% were intraprogrammatic and 10% were interprogrammatic. The scientific goals of the program are highlighted by its themes of (1) reducing cancer risk and (2) improving cancer-related care, both of which are tied together by the cross-cutting theme of alleviating disparities. CPC continues to achieve significant impact in these areas as evidenced by the program’s accomplishments of: translating MCC basic science findings into clinical trials for a novel smoking cessation therapy (now in phase IIa clinical trials in collaboration with the University of Pittsburgh Cancer Institute); informing the FDA and WHO tobacco policy on modified-risk tobacco products such as e-cigarettes with CPC’s first multi-PI P50 grant; decreasing cancer risk through obesity control in high-risk populations– adolescents and African Americans; improving cancer screening decision making; enhancing patient and caregiver experience with cancer care; identifying Medicaid and other policy effects on access to care; identifying barriers to African American enrollment in clinical research trials; and developing methods to overcome these barriers. In line with the NCI priority to foster multidisciplinary research, MCC has facilitated cross-cutting collaborations by generating an award program dedicated to CPC interprogrammatic pilot projects, several of which have recently led to large externally-funded grant projects. Value is added by MCC shared resources and CPC-sponsored education and training through monthly seminars, interprogrammatic research retreats, competitive CPC pilot grants, and through support of student and trainee fellowships. In summary, the CPC program is a vital, dynamic, and growing program within MCC, which addresses the unique needs of the MCC catchment area, as well as the nation more generally. The program, with its vibrant research agenda, engaged multidisciplinary membership, and ongoing support from MCC is well poised to continue to build upon the impact of its high-quality basic science, clinical, policy, and outcomes research.