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HPV Oropharyngeal cancer and screening in Gay and Bisexual Men

男同性恋和双性恋男性的 HPV 口咽癌和筛查

基本信息

批准号：
10179342
负责人：
MICHAEL W ROSS
金额：
$ 34.74万
依托单位：
UNIVERSITY OF MINNESOTA
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-09-01 至 2023-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10179342
关键词：
Address Age Alcohols Area Assessment tool Attitude Awareness Back Behavioral Belief Biological Bisexual Cancer Detection Cancer Etiology Cellular Phone Cities Client Clinical Data Data Collection Dental Dental Care Dental Hygienists Dentists Detection Diagnosis Early Diagnosis Early treatment Education Effectiveness Ensure Evaluation Federally Qualified Health Center Frequencies Funding Gays Guidelines HIV HIV Infections Health Health Professional Heavy Drinking High Prevalence Human Papilloma Virus Vaccination Human Papillomavirus Human papilloma virus infection Human papillomavirus 16 Incidence Infection International Intervention Interview Knowledge Lesbian Gay Bisexual Transgender Low income Malignant Neoplasms Medical Mouth Abnormalities Nurses Oral Oral Examination Oral Sex Oral cavity Oropharyngeal Patients Persons Pharyngeal structure Physician Assistants Physicians Population Prevalence Prevention program Primary Prevention Private Practice Privatization Prognosis Protocols documentation Provider Public Health Research Respondent Risk Risk Behaviors Risk Factors Sampling Screening for cancer Secondary Prevention Self Assessment Self-Examination Site Smoking Specialist Surveys Survival Rate Symptoms Target Populations Telecommunications Telemedicine Texas Training United States National Institutes of Health Vaccinated Visit Visual acceptability and feasibility base cancer risk early screening ethnic diversity ethnic minority population experience impression improved innovation male malignant mouth neoplasm malignant oropharynx neoplasm medical examination men men who have sex with men metropolitan nicotine use phase I trial programs racial and ethnic racial diversity recruit remote patient monitoring screening screening guidelines self testing sexual minority sexual risk behavior socioeconomic diversity tumor uptake willingness

项目摘要

Abstract: Oropharyngeal cancer (OPCa) caused by Human Papilloma Virus infection has risen steadily in the past two decades. It is primarily associated with sexual risk behavior, specifically oral sex in MSM. Oral cancers associated with HPV, when detected early by oral examination by medical and dental practitioners, can be successfully diagnosed and treated, with significantly increased survival. To improve screening and detection, we propose a 3-part study. First, to interview medical and dental teams, both private and in a Federally Qualified Health Center, with large GBM client bases in two large US metropolitan areas, to understand the screening and reasons for screening for oropharyngeal cancers and guidelines used. Second, we will survey 1500 GBM in the US to determine knowledge and beliefs about OPCa, HPV vaccination knowledge and uptake, experiences with providers and screening, and willingness to engage in screening. Finally, given the potential visibility of OPCa tumors to oral visual examination, we will assess the feasibility of a remote patient monitoring telecommunications-based intervention. We will ask GBM to take oral “selfies” with a cell phone, of sufficient clarity in regard to standard oral landmarks, and to send these photos to a central site where assessment can be made by an OPCa specialist clinician. The interview and survey data, and the feasibility results will be used to inform increased screening guidelines and education for both GBM and the practitioners who treat them, and to develop programs for increased awareness and screening in GBM. The acceptability, feasibility and preliminary efficacy data will assess whether self-examination and oral “selfies” are realistic and have the necessary clarity to form the basis of a telemedicine- based screening campaign for those at risk of developing OPCa, and its rigorous evaluation.

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