2/5 The Cumulative Risk of Substance Exposure and Early Life Adversity on Child Health Development and Outcomes
2/5 物质暴露和早年不幸对儿童健康发展和结果的累积风险
基本信息
- 批准号:10199299
- 负责人:
- 金额:$ 19.38万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2019
- 资助国家:美国
- 起止时间:2019-09-30 至 2021-03-31
- 项目状态:已结题
- 来源:
- 关键词:AffectAmerican IndiansChild HealthCollectionCountryDataDevelopmentDevicesElectrocardiogramElectroencephalographyEthicsEuropeanGestational DiabetesGoalsHealth PersonnelHealth PromotionHome environmentHospitalsIncidenceInvestigationKnowledgeLeadMaternal HealthMaternal MortalityMental DepressionMonitorMotivationOutcomePolysomnographyPopulationPre-EclampsiaPregnancyPregnancy ComplicationsPregnant WomenReportingResearch SupportRiskRisk FactorsScheduleSleepSleep disturbancesUnited StatesVariantVisitWomen&aposs Healthbasecost effectiveearly life adversityethnic minority populationexperiencehealth disparityhealth equityhigh riskimprovedmaternal outcomematernal riskmodifiable riskmonitoring devicemortalitypandemic diseaseperinatal periodpregnancy hypertensionracial and ethnicsevere maternal morbiditysleep healthstudy populationtelehealthtoolwearable device
项目摘要
Project Summary/Abstract
In the United States, rates of maternal mortality and severe maternal morbidities are higher than almost
all European countries and provide one of the starkest examples of women's health disparities. One
modifiable risk factor associated with multiple maternal complications during pregnancy is sleep health.
Poor sleep health in the perinatal period has been found to be associated with several conditions
known to increase the risk for maternal health complications and mortality, such as gestational
diabetes, pregnancy-induced hypertension, preeclampsia, and depression. Additionally, greater risk
incidence of poor sleep reports occurs among racial/ethnic minorities. Nonetheless, sleep health
changes are often regarded by pregnant women and healthcare providers as “normal” and there is a
lack of understanding on what constitutes normal/abnormal variations in sleep health during pregnancy.
This knowledge gap in part, derives from the lack of cost-effective, easy-to use and reliable sleep
monitoring devices that can be used in the home. The current proposal will investigate the feasibility of
using wearable devices that acquires 2-lead EEG and ECG to monitor sleep during pregnancy and
specifically in an American Indian population at high risk for poor maternal outcome. Our hypotheses
are that: 1) we will have a positive experience in home delivery and collection of devices in the general
study population across all racial ethic groups and 2) we will collect a minimum of 75% usable data for
the overnight recordings, which will allow us to acquire and derive sleep health metrics using a
validated AI platform.
Our goal is to establish if wearable solutions would provide viable alternatives to sleep lab assessments
and more invasive in-home monitor solutions. This investigation is particularly relevant given the current
pandemic, which has affected the ability and motivation for pregnant women to schedule visits for
hospital-based studies, making telehealth solutions a preferable solution.
In conclusion, sleep has been shown to be a modifiable risk factor and the availability of practical tools
to assess sleep health in the home environment will afford the opportunity to improve maternal health,
as outlined in the IMPROVE initiative goals, to support research on how to mitigate preventable
maternal mortality, decrease severe maternal morbidity, and promote health equity in the U.S.
项目摘要/摘要
在美国,孕产妇死亡率和严重的孕产妇病情比几乎高于
所有欧洲国家,并提供了妇女健康分配最明显的例子之一。一
与怀孕期间多发性并发症相关的可修改风险因素是睡眠健康。
在围产期的睡眠健康状况不佳与多种情况有关
已知会增加生物健康并发症和死亡率的风险,例如妊娠
糖尿病,妊娠诱发的高血压,先兆子痫和抑郁症。另外,风险更大
睡眠不良报告的发病率发生在种族/族裔少数群体中。尽管如此,睡眠健康
孕妇和医疗保健提供者经常将变化视为“正常”,并且有一个
缺乏对怀孕期间睡眠健康正常/异常变化的理解。
这些知识差距部分源于缺乏成本效益,易于使用和可靠的睡眠
可以在家庭中使用的监视设备。当前的提议将调查
使用可穿戴设备,这些设备获得2铅EEG和ECG,以监测怀孕期间的睡眠
特别是在美洲印第安人人口较差的美洲人口中。我们的假设
是:1)我们将在送货上门和一般设备收集方面具有积极的经验
研究所有种族伦理群体的人群和2)我们将收集至少75%的可用数据
隔夜录音,这将使我们能够使用一个
已验证的AI平台。
我们的目标是确定可穿戴解决方案是否可以为睡眠实验室评估提供可行的替代方案
以及更具侵入性的家庭监测率解决方案。鉴于当前的投资特别重要
大流行,影响了孕妇安排访问的能力和动力
基于医院的研究,使远程医疗解决方案成为首选解决方案。
总之,睡眠已被证明是可修改的危险因素和实用工具的可用性
评估家庭环境中的睡眠健康将有机会改善母子健康,
如改进的倡议目标中概述的那样,支持有关如何减轻可预防的研究
孕产妇死亡率,降低严重的孕产妇发病率并促进美国的健康平等
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Amy J Elliott其他文献
Amy J Elliott的其他文献
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{{ truncateString('Amy J Elliott', 18)}}的其他基金
Maternal American-Indian Rural Community Health (MARCH)
美国-印度孕产妇农村社区健康(三月)
- 批准号:
10748656 - 财政年份:2023
- 资助金额:
$ 19.38万 - 项目类别:
South Dakota Pediatric Clinical Trials Network (SoDakPCTN)
南达科他州儿科临床试验网络 (SoDakPCTN)
- 批准号:
10923168 - 财政年份:2020
- 资助金额:
$ 19.38万 - 项目类别:
South Dakota Pediatric Clinical Trials Network (SoDakPCTN)
南达科他州儿科临床试验网络 (SoDakPCTN)
- 批准号:
10625726 - 财政年份:2020
- 资助金额:
$ 19.38万 - 项目类别:
South Dakota Pediatric Clinical Trials Network (SoDakPCTN)
南达科他州儿科临床试验网络 (SoDakPCTN)
- 批准号:
10242215 - 财政年份:2020
- 资助金额:
$ 19.38万 - 项目类别:
South Dakota Pediatric Clinical Trials Network (SoDakPCTN)
南达科他州儿科临床试验网络 (SoDakPCTN)
- 批准号:
10474477 - 财政年份:2020
- 资助金额:
$ 19.38万 - 项目类别:
South Dakota Pediatric Clinical Trials Network (SoDakPCTN)
南达科他州儿科临床试验网络 (SoDakPCTN)
- 批准号:
10064263 - 财政年份:2020
- 资助金额:
$ 19.38万 - 项目类别:
2/5 The Cumulative Risk of Substance Exposure and Early Life Adversity on Child Health Development and Outcomes
2/5 物质暴露和早年不幸对儿童健康发展和结果的累积风险
- 批准号:
10017367 - 财政年份:2019
- 资助金额:
$ 19.38万 - 项目类别:
2/5 The Cumulative Risk of Substance Exposure and Early Life Adversity on Child Health Development and Outcomes
2/5 物质暴露和早年不幸对儿童健康发展和结果的累积风险
- 批准号:
9899486 - 财政年份:2019
- 资助金额:
$ 19.38万 - 项目类别:
Environmental Influences on Child Health Outcomes in the Northern Plains Safe Passage Study Cohort
环境对北部平原安全通道研究队列儿童健康结果的影响
- 批准号:
10442792 - 财政年份:2016
- 资助金额:
$ 19.38万 - 项目类别:
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