South Dakota Pediatric Clinical Trials Network (SoDakPCTN)

SoDakPCTN项目摘要/摘要 南达科他州儿科临床试验网络（SoDakPCTN）的目的是 利用过去十年来儿科研究的热情和增长来建立能力 和临床试验的技能。这一势头是通过以下方面的积极合作发展起来的： 过去二十年来，在部落国家、卫生诊所和医院开展的以社区为基础的研究 帮助改善南达科他州儿童的健康状况。虽然南达科他州一直是一个地区性的 大规模纵向多中心观察性研究的领导者（例如，安全通道研究， ECHO儿科队列），参与儿科临床研究的机会已经 有限公司SoDakPCTN将被安置在Avera Health系统内，这是一个大型卫生系统 包括南达科他州100个社区的300个地点和四个地区 周边国家。阿维拉卫生系统包括35家医院和34个社区， 关键的医院。Avera卫生系统和合作伙伴非常适合开展 高质量的儿科临床试验，专门针对农村，边境和美洲印第安人（AI） 整个南达科他州的人口。儿科和社区研究中心（CPCR） 致力于建立一个强大的儿科研究基础设施，允许大， 已经在全国各地的诊所、医院和社区进行的规模纵向研究 在苏福尔斯、拉皮德城和松树岭设有办事处。 SoDakPCTN将围绕三个具体目标建立。首先，建立在现有的儿科 研究基础设施，以创造一个协作环境，支持最先进的 儿科临床试验在住院，门诊，和社区为基础的设置。二是支持 初级研究者和研究人员在开展儿科临床研究方面的职业发展 通过导师制、专业发展机会和潜力介绍进行试验 医院、诊所和社区合作伙伴。第三，利用社区参与的方法， 研究传播策略，并将研究结果转化为临床和社区 利益攸关方改进知识和做法。

SoDakPCTN Project Summary / Abstract The purpose of the South Dakota Pediatric Clinical Trials Network (SoDakPCTN) is to leverage the enthusiasm and growth in pediatric research over the last decade to build capacity and skills in clinical trials. This momentum was developed through active collaborations over the past two decades in community-based research with tribal nations, health clinics and hospitals to help improve the health of children in South Dakota. While South Dakota has been a regional leader in large scale longitudinal multi-site observational studies (e.g., Safe Passage Study, ECHO pediatric cohort), opportunities to participate in pediatric clinical research have been limited. SoDakPCTN will be housed within the Avera Health system, a large health system comprised of 300 locations in 100 communities throughout South Dakota and areas of the four surrounding states. The Avera Health system includes 35 hospitals and 34 community and critical access hospitals. The Avera health system and partners are ideally suited to conduct high quality pediatric clinical trials that specifically reach rural, frontier, and American Indian (AI) populations across South Dakota. The Center for Pediatric and Community Research (CPCR) at Avera has worked to establish a robust pediatric research infrastructure that allows for large - scale longitudinal studies that already occur within clinics, hospitals and communities across the state, with offices in Sioux Falls, Rapid City and Pine Ridge. SoDakPCTN will be built around three specific aims. First, build upon existing pediatric research infrastructure to create a collaborative environment that supports state -of-the-art pediatric clinical trials in inpatient, outpatient, and community-based settings. Second, support career development for junior investigators and research staff in conducting pediatric clinical trials through mentorship, professional development opportunities, and introduction to potential hospital, clinic, and community partners. Third, using a community engaged approach, develop research dissemination strategies and translate research findings to clinical and community stakeholders to improve knowledge and practice.