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Impact of Marijuana Legalization: Comparison of Two Longitudinal Twin Cohorts

大麻合法化的影响：两个纵向双胞胎群体的比较

基本信息

批准号：
10192397
负责人：
JOHN K. HEWITT
金额：
$ 15.43万
依托单位：
UNIVERSITY OF COLORADO DENVER
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-09-01 至 2022-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10192397
关键词：
Adolescence Adult Affect Age Alcohol consumption Alcohol or Other Drugs use Alcohols Anxiety Behavior COVID-19 COVID-19 pandemic Cannabis Cessation of life China Colorado Data Dependence Diagnosis Disease Exposure to Financial Hardship Functional disorder Gender Goals Grant Home environment Individual Individual Differences International Legal Legal Status Marijuana Marijuana Abuse Market Research Measurement Medical Marijuana Mental Depression Mental Health Mental disorders Minnesota Occupational Participant Pattern Property Psychopathology Reporting Research Risk Sales Sample Size Sampling Social Distance Stress Substance Addiction Substance Use Disorder Testing Time Twin Multiple Birth Twin Studies Unemployment United States World Health Organization base behavioral disinhibition cohort coronavirus disease drinking drinking behavior marijuana legalization marijuana use novel virus parent grant parent project psychosocial public health emergency resilience social stressor substance misuse

项目摘要

This supplemental grant proposes to add questions to extend the aims of the parent project by collecting additional data related to COVID-19 including financial hardships, social/interpersonal problems, stress, mental health, and substance use changes. Data will also be collected on whether participants are essential workers, were exposed to COVID-19, or have been diagnosed with COVID-19. Parent grant Aim 1: Effect of RML on substance use/misuse, mental health, & psychosocial function Aim 1 extended: Effect of COVID-19 pandemic and RML on substance use/misuse, mental health & psychosocial function. We will test the hypothesis that access to RML increases the likelihood that the stress and disruption associated with COVID-19 will lead to increased marijuana use and abuse. Relatedly, we will test the extent to which increased marijuana use, related to RML and stress/disruptions from COVID-19, is accompanied by increases in other substance use, mental health disorders, or psychosocial dysfunction. Parent grant Aim 2: Individual differences in the effect of RML Aim 2 extended: Examine individual differences in the effect of COVID-19 pandemic and RML. Examine individual differences in the effects of COVID-19 and legalization by leveraging parallel multi-wave longitudinal twin studies in CO and MN, which both began collecting substance use, psychopathology, and psychosocial function during the twins' adolescence. This supplemental assessment will allow us to: a) identify how COVID-19 differentially impacts individuals depending on legalization and prior exposure to marijuana; b) examine how individuals differ in their vulnerability and resilience to the effects COVID-19, in the context of legalization, based on their individual level of risk (e.g., prior diagnosis of anxiety or depression); and c) examine if there are differential associations between COVID-19 and substance use/dependence, mental health, and psychosocial problems depending on legalization status and gender.

此补充奖助金建议通过收集来增加问题以扩展母计划的目标