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中文摘要
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摘要 白血病孢子发育研究计划(DRP)的总体目标是招募和 支持白血病的发展研究项目,以获得未来的同行评审资金和/或未来的 独立的SPORE项目。资助的研究项目包括基础研究、临床研究、 研究、流行病学研究以及白血病的癌症预防和控制研究。支助的项目 在DRP下,将扩大转化研究的范围,增加研究人员的数量 致力于白血病研究DRP将与职业提升计划(CEP)协同工作 协助培养初级调查员,征聘和辅导少数族裔调查员, investigators.为实现这些目标,提出了以下具体目标 目标1.支持白血病的发展研究项目,以便将来纳入全面 SPORE项目和其他主要同行评审资金的申请。新的研究项目将 每年征集。每年共承诺300 000美元,以支持合并的CEP和DRP (包括来自SPORE基金的CEP和DRP每年各50,000美元,以及每年200,000美元的匹配资金 机构资金)。DRP奖励将高达70,000美元,为期1年,允许竞争性续订, 第二年,资金允许。资金可用于薪金支助或实验室用品。 目标2.促进基础和临床研究人员之间的合作。DRP椅子将促进 基础和临床研究人员之间的互动,通过共享每周会议,年度孢子 务虚会和小组会议。 目标3。为初级教员提供指导。所有提交发育研究的研究者 项目将收到一份书面的科学和统计审查,DRP主席将参加讨论 项目详细。在适当的情况下,导师将确定与初级教师。所有DRP 获奖者将每年两次向SPORE指导委员会介绍他们的研究进展。 目标4。促进妇女、少数民族和残疾研究者参与临床研究, 白血病研究和促进招募少数群体参加白血病临床试验。
英文摘要
ABSTRACT The overall goal of the Leukemia SPORE Developmental Research Program (DRP) is to recruit and support developmental research projects in leukemia for future peer-reviewed funding and/or future independent SPORE projects. The types of studies to be supported include projects in basic research, clinical research, epidemiologic studies, and cancer prevention and control research in leukemia. Projects supported under the DRP will expand the scope of translational research and increase the number of investigators committed to leukemia research. The DRP will work in tandem with the Career Enhancement Program (CEP) to assist in the development of junior investigators and in the recruitment and mentoring of minority investigators. To accomplish these goals, the following specific aims are proposed Aim 1. To support developmental research projects in leukemia for future incorporation as full SPORE projects and for applications for other major peer-reviewed funding. New research projects will be solicited annually. A total of $300,000 has been committed per year to support the combined CEP and DRP (including $50,000 per year each for the CEP and DRP from SPORE funds and $200,000 per year of matching institutional funds). DRP awards will be for up to $70,000 for 1 year, with a competitive renewal allowed for a second year of funding allowed. Funds may be used for salary support or laboratory supplies. Aim 2. To foster collaborations between basic and clinical researchers. The DRP chairs will facilitate interaction between basic and clinical researchers through shared weekly meetings, the annual SPORE retreat, and small group meetings. Aim 3. To provide mentoring to junior faculty. All investigators submitting developmental research projects will receive a written scientific and statistical review, and the DRP chairs will be available to discuss the projects in detail. Where appropriate, mentors will be identified to work with junior faculty. All DRP awardees will present their research progress to the SPORE steering committee twice per year. Aim 4. To promote participation of women, minorities, and disabled investigators in clinical leukemia research and to promote recruitment of minorities to clinical leukemia trials.
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Identification of new genetic causes of congenital neutropenia
  • 批准号:
    10621903
  • 项目类别:
  • 资助金额:
    $39.38万
  • 财政年份:
    2020
  • 负责人:
    Daniel C Link
  • 依托单位:
Identification of new genetic causes of congenital neutropenia
  • 批准号:
    10159977
  • 项目类别:
  • 资助金额:
    $39.38万
  • 财政年份:
    2020
  • 负责人:
    Daniel C Link
  • 依托单位:
Identification of new genetic causes of congenital neutropenia
  • 批准号:
    10399626
  • 项目类别:
  • 资助金额:
    $39.38万
  • 财政年份:
    2020
  • 负责人:
    Daniel C Link
  • 依托单位:
Single Cell Spatial Characterization of the Human Bone Marrow Microenvironment
  • 批准号:
    10115110
  • 项目类别:
  • 资助金额:
    $19.69万
  • 财政年份:
    2020
  • 负责人:
    Daniel C Link
  • 依托单位:
海外基金