A Spatially Resolved Molecular Atlas of Human Endothelium

抽象协调核 ​加州理工大学组织图谱中心的协调核心(CC)将负责 协调我们TMC内部的活动，以及一般行政职能，以支持我们的TMC。它还将 负责跟踪有关生物样品收集和数据生成的进度，收集 以及元数据的组织，确保生物标本和数据以及数据/元数据的适当质量控制 提交到蜂巢和其他适当的门户网站。最后，我们的CC将负责确保​ 与HuBMAP联盟和更广泛的研究社区进行协调。这项建议的个人资料显示 在合作研究、管理复杂的多机构方面有丰富的经验和记录 成功参与大规模基因组学联盟的项目(​，例如​Encode，4DN，Center for 孟德尔基因组学)，以及开发广泛使用的开源软件和数据集(​，例如​袖扣， 单片，虫、蝇、鼠的细胞图谱)。我们将依靠这一专业知识在我们的 集团以及与财团和社区的合作，并确保我们在以下方面实现我们的所有目标 Biosecimen收集、数据生成、质量评估以及将数据和元数据提交给蜂巢和 研究社区以最大限度地发挥这一计划的影响。

ABSTRACT - COORDINATION CORE The Coordination Core (CC) of the ​Caltech-UW Tissue Mapping Center (TMC) will be responsible for coordinating activities within our TMC, and for general administrative functions to support our TMC. It will also be responsible for tracking progress with respect to biospecimen collection and data generation, the collection and organization of metadata, ensuring appropriate QC of both biospecimens and data, and data/metadata submission to the HIVE and other appropriate portals. Finally, our CC will be responsible for ​ensuring coordination with the HuBMAP Consortium and the wider research community. The PIs of this proposal have extensive experience and track records of collaborative research, of managing complex multi-institutional projects, of successfully participating in large scale consortia in genomics (​e.g. ​ENCODE, 4DN, Centers for Mendelian Genomics), and of developing widely used open-source software and datasets (​e.g. ​Cufflinks, Monocle, cell atlases of worm, fly, mouse). We will rely on this expertise to effectively coordinate within our group as well as with the consortium and community, and to ensure that we meet all of our goals in terms of biospecimen collection, data generation, quality assessment, and data & metadata submission to the HIVE and research community to maximize the impact of this program.