Johns Hopkins HIV and Heart, Lung, Blood & Sleep Disorders Training Program (H3TP)

项目摘要 霍普金斯艾滋病毒和心脏，肺，血液和睡眠障碍培训计划的长期目标 （H3 TP）是培养和发展一支优秀的调查人员队伍，他们将促进知识和 改善艾滋病毒感染者（PLWH）和合并心脏、肺、血液和 睡眠（HLBS）障碍。这一目标与NHLBI的使命和艾滋病研究办公室直接相关 高度优先的研究问题，以解决艾滋病毒感染的老年人的合并症。在这个新的K-12提案中， 我们将通过实现以下具体目标来实现这一目标：（1）提供一个 为博士后研究员和初级教师提供严格的，有指导的培训经验，以开发研究 利用约翰霍普金斯HIV HLBS的丰富资源 研究者可以访问关于特征明确的患者和队列人群的数据，使受训者项目能够 快速启动和执行;（3）提供杰出的方法和分析专业知识， 促进研究成功;（4）让学员参与高素质的合作研究项目， 重要的问题和测试有意义的假设下，监督全国知名的多， 学科教师;（5）整合多层次和个性化的指导，为每个学员发展 有意义的奖学金和成功的调查生涯;（6）评估该计划的成果 并进行修改以最大限度地提高其成功率。 在这个提案中，我们利用了约翰霍普金斯大学杰出的HIV和HLBS研究社区，包括 现有的临床和转化基础设施，以支持培训和研究，高生产力的计划 教师，充满活力的跨部门和跨部门的多学科合作，优秀的机构 致力于博士后和早期研究人员的高水平培训。通过这些方案， 根据我们的特点，我们预计将有一个强大的候选人库和优秀的结果为我们的学员。 我们的计划结合了在一个多学科的矩阵内的调查单一领域的强化培训 合作，并将支持博士后和入门级教师学员1-3年。广泛的 培训机会由一个由大量赠款支持的大型教师互动网络提供 portfolio.体验的核心是主要导师、共同导师和 围绕具体的研究项目。个性化的培训体验，通过使用个人指导 发展计划，将由正式的课程工作，可以导致研究生学位，和一个补充， 一系列丰富活动，包括参加核心H3 TP论坛，与一群类似的同行学习， 分阶段受训人员、个别会议、负责任的研究行为培训、职业规划、补助金 写作和手稿准备。多点反馈和过程措施的监控将 通知和指导我们新制定的计划，以确保我们的目标得以实现。

Project Summary The long-term objective of the Hopkins HIV and Heart, Lung, Blood and Sleep Disorders Training Program (H3TP) is to train and develop a cadre of outstanding investigators who will advance knowledge and improve outcomes for people living with HIV infection (PLWH) and comorbid heart, lung, blood and sleep (HLBS) disorders. This goal is directly relevant to the NHLBI mission and to the Office of AIDS Research high priority research issues to address comorbidities in the setting of aging with HIV. In this new K-12 proposal, we will be accomplish this objective through implementation of the following Specific Aims: (1) Provide a rigorous, mentored training experience for postdoctoral fellows and junior faculty to develop a research niche in HLBS comorbidities in HIV; (2) Utilize the rich resources available to Johns Hopkins HIV HLBS investigators to access data on well-characterized patient and cohort populations to enable trainee projects to be rapidly initiated and executed; (3) Provide access to outstanding methodologic and analytic expertise to facilitate research success; (4) Engage trainees in high caliber collaborative research projects that address important questions and test meaningful hypotheses under the supervision of nationally-renowned multi- disciplinary faculty; (5) Integrate multi-layered and individualized mentorship for each trainee to develop meaningful scholarship and a successful investigative career; and (6) Assess the outcomes of the program and make modifications to maximize its success. In this proposal, we leverage the outstanding community of HIV and HLBS research at Johns Hopkins including existing clinical and translational infrastructure to support training and research, highly productive program faculty, vibrant interdepartmental and interdivisional multidisciplinary collaborations, excellent institutional commitment to high level training of postdoctoral and early stage investigators. With these program characteristics, we anticipate a robust pool of candidates and outstanding outcomes for our trainees. Our program combines intensive training in a single area of investigation within a matrix of multidisciplinary collaborations and will support post-doctoral and entry-level faculty trainees for 1-3 years. A wide range of training opportunities are provided by a large interactive network of faculty supported by a substantial grant portfolio. The core of the experience is the close relationship between a primary mentor, co-mentors, and the trainee around specific research projects. A personalized training experience, guided through use of individual development plans, will be supplemented by formal course work which can lead to a graduate degree, and a series of enrichment activities including participation in a core H3TP forum, peer learning with a cohort of similar- staged trainees, individualized conferences, training in responsible research conduct, career planning, grant writing, and manuscript preparation. Multiple points of feedback and monitoring of process measures will inform and guide our newly constituted program to ensure our objectives are achieved.