The effect of a housing mobility program on environmental exposures and asthma morbidity among low-income minority children

住房流动计划对低收入少数族裔儿童的环境暴露和哮喘发病率的影响

• 批准号: 10202894
• 负责人: Corinne Keet
• 金额: $ 29.51万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-01 至 2021-08-12
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10202894
• 关键词: 2019-nCoV; Adult; Affect; African American; Air; Air Pollution; Allergens; Antibodies; Asthma; COVID-19; COVID-19 pandemic; Cessation of life; Child; China; Data; Disease; Economic Recession; Economics; Enrollment; Environmental Exposure; Goals; Home environment; House Dust; Household; Housing; Individual; Indoor Air Quality; Infection; Italy; Link; Long-Term Effects; Low income; Maryland; Measurement; Measures; Methods; Minority; Monitor; Morbidity - disease rate; Participant; Pattern; Phenotype; Population; Positioning Attribute; Prevalence; Questionnaires; Respiratory physiology; Risk; Saliva; Schools; Severities; Severity of illness; Shelter facility; Standardization; Symptoms; Time; Tobacco use; Travel; Unemployment; Workplace; ambient air pollution; cohort; comorbidity; environmental tobacco smoke; experience; indoor allergen; indoor exposure; indoor pollutant; infection rate; member; minority children; novel; novel coronavirus; pandemic disease; parent grant; pollutant; programs; telework

Abstract Minority populations in the U.S. are much more likely to be infected with the novel coronavirus SARS-CoV2 and experience severe COVID-19 disease. In this proposal, we leverage our existing cohort of low-income children with asthma who participate in a housing mobility program to characterize rates of SARS-CoV2 infection and disease among participating children and their household members, to explore the relationship between indoor allergen and pollutant exposures, including second-hand smoke and SARS-CoV2 infection and disease, and to assess the impact of pandemic conditions on indoor exposures relevant to asthma among this population. This cohort presents a unique opportunity to study SARS-CoV2 within a cohort of children with well phenotyped asthma and well-characterized indoor exposures.

抽象的 美国少数族裔人口更有可能感染新型冠状病毒SARS-COV2 并经历了严重的Covid-19疾病。在此提案中，我们利用现有的低收入队列 参加住房行动计划的哮喘儿童以表征SARS-COV2的比率 参与儿童及其家庭成员的感染和疾病，探索这种关系 在室内过敏原和污染物暴露之间，包括二手烟和SARS-COV2感染以及 疾病，并评估大流行状况对与哮喘相关的室内暴露的影响 人口。该队列为研究SARS-COV2的独特机会在有井的儿童中 表型哮喘和良好的室内暴露。