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The effect of a housing mobility program on environmental exposures and asthma morbidity among low-income minority children

住房流动计划对低收入少数族裔儿童的环境暴露和哮喘发病率的影响

基本信息

批准号：
10202894
负责人：
Corinne Keet
金额：
$ 29.51万
依托单位：
JOHNS HOPKINS UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-07-01 至 2021-08-12
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10202894
关键词：
2019-nCoV Adult Affect African American Air Air Pollution Allergens Antibodies Asthma COVID-19 COVID-19 pandemic Cessation of life Child China Data Disease Economic Recession Economics Enrollment Environmental Exposure Goals Home environment House Dust Household Housing Individual Indoor Air Quality Infection Italy Link Long-Term Effects Low income Maryland Measurement Measures Methods Minority Monitor Morbidity - disease rate Participant Pattern Phenotype Population Positioning Attribute Prevalence Questionnaires Respiratory physiology Risk Saliva Schools Severities Severity of illness Shelter facility Standardization Symptoms Time Tobacco use Travel Unemployment Workplace ambient air pollution cohort comorbidity environmental tobacco smoke experience indoor allergen indoor exposure indoor pollutant infection rate member minority children novel novel coronavirus pandemic disease parent grant pollutant programs telework

项目摘要

Abstract Minority populations in the U.S. are much more likely to be infected with the novel coronavirus SARS-CoV2 and experience severe COVID-19 disease. In this proposal, we leverage our existing cohort of low-income children with asthma who participate in a housing mobility program to characterize rates of SARS-CoV2 infection and disease among participating children and their household members, to explore the relationship between indoor allergen and pollutant exposures, including second-hand smoke and SARS-CoV2 infection and disease, and to assess the impact of pandemic conditions on indoor exposures relevant to asthma among this population. This cohort presents a unique opportunity to study SARS-CoV2 within a cohort of children with well phenotyped asthma and well-characterized indoor exposures.

摘要美国少数民族更容易感染新型冠状病毒SARS-CoV 2 并经历严重的COVID-19疾病。在这项提案中，我们利用现有的低收入群体，参加住房流动性项目以表征SARS-CoV 2发病率的哮喘儿童调查参与计划的儿童及其家庭成员的感染和疾病情况，以探讨室内过敏原和污染物暴露之间的关系，包括二手烟和SARS-CoV 2感染，疾病，并评估大流行条件对哮喘相关室内暴露的影响，人口该队列提供了一个独特的机会，可以在一个健康儿童队列中研究SARS-CoV 2。表型哮喘和特征明确的室内暴露。