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The effect of a housing mobility program on environmental exposures and asthma morbidity among low-income minority children

住房流动计划对低收入少数族裔儿童的环境暴露和哮喘发病率的影响

基本信息

批准号：
10202894
负责人：
Corinne Keet
金额：
$ 29.51万
依托单位：
JOHNS HOPKINS UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-07-01 至 2021-08-12
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10202894
关键词：
2019-nCoV Adult Affect African American Air Air Pollution Allergens Antibodies Asthma COVID-19 COVID-19 pandemic Cessation of life Child China Data Disease Economic Recession Economics Enrollment Environmental Exposure Goals Home environment House Dust Household Housing Individual Indoor Air Quality Infection Italy Link Long-Term Effects Low income Maryland Measurement Measures Methods Minority Monitor Morbidity - disease rate Participant Pattern Phenotype Population Positioning Attribute Prevalence Questionnaires Respiratory physiology Risk Saliva Schools Severities Severity of illness Shelter facility Standardization Symptoms Time Tobacco use Travel Unemployment Workplace ambient air pollution cohort comorbidity environmental tobacco smoke experience indoor allergen indoor exposure indoor pollutant infection rate member minority children novel novel coronavirus pandemic disease parent grant pollutant programs telework

项目摘要

Abstract Minority populations in the U.S. are much more likely to be infected with the novel coronavirus SARS-CoV2 and experience severe COVID-19 disease. In this proposal, we leverage our existing cohort of low-income children with asthma who participate in a housing mobility program to characterize rates of SARS-CoV2 infection and disease among participating children and their household members, to explore the relationship between indoor allergen and pollutant exposures, including second-hand smoke and SARS-CoV2 infection and disease, and to assess the impact of pandemic conditions on indoor exposures relevant to asthma among this population. This cohort presents a unique opportunity to study SARS-CoV2 within a cohort of children with well phenotyped asthma and well-characterized indoor exposures.

抽象的美国的少数族裔更有可能感染新型冠状病毒 SARS-CoV2 并患有严重的 COVID-19 疾病。在本提案中，我们利用现有的低收入群体参加住房流动计划以了解 SARS-CoV2 感染率的哮喘儿童参与儿童及其家庭成员的感染和疾病，探讨其关系室内过敏原和污染物暴露之间的关系，包括二手烟和 SARS-CoV2 感染，疾病，并评估大流行病对与哮喘相关的室内暴露的影响人口。该队列提供了在一组患有健康问题的儿童中研究 SARS-CoV2 的独特机会表型哮喘和特征明确的室内暴露。