The effect of a housing mobility program on environmental exposures and asthma morbidity among low-income minority children
住房流动计划对低收入少数族裔儿童的环境暴露和哮喘发病率的影响
基本信息
- 批准号:10296756
- 负责人:
- 金额:$ 67.6万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2016
- 资助国家:美国
- 起止时间:2016-03-01 至 2026-06-30
- 项目状态:未结题
- 来源:
- 关键词:AddressAdultAllergensAsthmaBaltimoreBirthCaregiver BurdenChildChildhood AsthmaCommunitiesDataDiscriminationEnrollmentEnvironmental ExposureExposure toFollow-Up StudiesGrowthHealthHomeHousingInterventionLife ExpectancyLong-Term EffectsLow incomeLungMeasuresMediatingMedicaidMorbidity - disease rateNatural HistoryNeighborhoodsOutcomeParentsParticipantPlant RootsPoliciesPollutionPositioning AttributePovertyProspective cohort studyPsychosocial StressPublic HealthRoleStressSymptomsTimeUrban PopulationUrsidae Familybaseburden of illnesscohortdevelopment policyethnic minority populationfamily supportfollow-upimprovedindoor exposureinner cityminority childrenmouse allergenpoor communitiesprogramspulmonary functionstressortherapy designtoolurban childrenurban setting
项目摘要
Children living in poor-urban neighborhoods bear a high burden of asthma morbidity, and there is strong
evidence that housing-related environmental exposures such as pest allergens are a major driver of this
excess asthma morbidity. Historic residential discrimination together with systemic disinvestment in
neighborhoods have contributed to poor neighborhood and housing conditions, which make successful
mitigation of housing-related exposures difficult, and in many cases, impossible. In contrast, housing mobility
programs, where families are supported in moving to less segregated communities, may address the root-
causes of the exposures that drive asthma disparities, while also serving as a tool by which we can parse the
role of various housing and neighborhood exposures and understand their long-term effects on asthma. In our
Mobility Asthma Project (MAP, R01 ES026170-05), children with asthma are followed before and after moving
from high-poverty segregated neighborhoods to low-poverty neighborhoods. We have found, so far, that with
moving, allergen levels and asthma outcomes are markedly reduced. This suggests that housing policy may be
a tool to reduce asthma disparities. However, while these initial findings strongly support the benefit of housing
mobility programs on short-term asthma outcomes, additional questions have emerged which can only be
answered by follow-up of this unique cohort. Our aims here are (1) To compare long-term (4-7 years) asthma
morbidity and home exposures between low-income, minority children with asthma who move to low-poverty
neighborhoods with similar children living in high-poverty neighborhoods, (2) To determine if moving from a
high- to a low-poverty neighborhood is associated with improved lung function growth among the original MAP
participants by repeatedly assessing lung function up to 4-7 years post-move and comparing their lung function
trajectories with a similar population from the URECA cohort and (3) To examine the role of stress, measured
by: a) exposure to neighborhood stressors, b) parental/caregiver stress, and c) child stress in the relationships
between indoor exposures, moving, and asthma morbidity and lung function. The proposed MAP Follow-Up
Study is poised to advance our understanding of the long-term effects of living in poor quality housing in high
poverty neighborhoods on asthma and lung function growth and directly inform the development of policy-
oriented interventions, such as expansion of housing mobility programs, which show great promise for
reducing the disproportionate burden of asthma among minority children with asthma.
生活在贫困城市社区的儿童承担着哮喘发病率的沉重负担,而且有很强的
有证据表明,与住房有关的环境暴露,如害虫过敏原,是这一问题的主要驱动因素
哮喘发病率过高。历史上的居住歧视以及对住房的系统性撤资
社区导致了贫困的社区和住房条件,这使得成功的
减少与住房有关的暴露是困难的,在许多情况下是不可能的。相比之下,住房流动性
支持家庭迁往隔离程度较低的社区的方案,可以解决根源问题,
导致哮喘差异的暴露原因,同时也作为一种工具,我们可以分析
不同的房屋和社区暴露的作用,并了解其对哮喘的长期影响。在我们
活动性哮喘项目(MAP,R 01 ES 026170 -05),对哮喘儿童在活动前后进行随访
从高度贫困的隔离社区到低贫困社区。到目前为止,我们发现,
移动,过敏原水平和哮喘的结果显着降低。这表明,住房政策可能是
减少哮喘差异的工具。然而,虽然这些初步调查结果强烈支持住房的好处,
流动性计划对短期哮喘的结果,其他问题已经出现,这只能是
通过对这一独特队列的随访来回答。我们的目的是(1)比较长期(4-7年)哮喘
低收入、少数民族哮喘儿童搬到低贫困地区后的发病率和家庭暴露
社区与类似的儿童生活在高贫困社区,(2)为了确定是否从一个
从高到低的贫困社区与原始MAP中肺功能的改善有关。
参与者通过反复评估肺功能长达4-7年后移动和比较他们的肺功能
轨迹与来自URECA队列的类似人群和(3)为了检查压力的作用,测量
通过:a)暴露于邻居的压力源,B)父母/照顾者的压力,和c)关系中的儿童压力
室内暴露、移动与哮喘发病率和肺功能之间的关系。拟议的MAP后续行动
这项研究准备推进我们对生活在高质量住房中的长期影响的理解,
贫困社区的哮喘和肺功能的增长,并直接告知政策的发展-
定向干预措施,如扩大住房流动方案,这些方案显示出很大的希望,
减少少数哮喘儿童的哮喘负担。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Corinne Keet其他文献
Corinne Keet的其他文献
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{{ truncateString('Corinne Keet', 18)}}的其他基金
The effect of a housing mobility program on environmental exposures and asthma morbidity among low-income minority children
住房流动计划对低收入少数族裔儿童的环境暴露和哮喘发病率的影响
- 批准号:
10202894 - 财政年份:2020
- 资助金额:
$ 67.6万 - 项目类别:
A prospective registry, biobank and observational study of food allergy
食物过敏的前瞻性登记、生物库和观察研究
- 批准号:
10363634 - 财政年份:2017
- 资助金额:
$ 67.6万 - 项目类别:
A prospective registry, biobank and observational study of food allergy
食物过敏的前瞻性登记、生物库和观察研究
- 批准号:
10581632 - 财政年份:2017
- 资助金额:
$ 67.6万 - 项目类别:
The effect of a housing mobility program on environmental exposures and asthma morbidity among low-income minority children
住房流动计划对低收入少数族裔儿童的环境暴露和哮喘发病率的影响
- 批准号:
10469499 - 财政年份:2016
- 资助金额:
$ 67.6万 - 项目类别:
Early Peanut Introduction: Translation to Clinical Practice
早期花生介绍:转化为临床实践
- 批准号:
9153173 - 财政年份:2016
- 资助金额:
$ 67.6万 - 项目类别:
The effect of a housing mobility program on environmental exposures and asthma morbidity among low-income minority children
住房流动计划对低收入少数族裔儿童的环境暴露和哮喘发病率的影响
- 批准号:
9888210 - 财政年份:2016
- 资助金额:
$ 67.6万 - 项目类别:
Early Peanut Introduction: Translation to Clinical Practice
早期花生介绍:转化为临床实践
- 批准号:
9491694 - 财政年份:2016
- 资助金额:
$ 67.6万 - 项目类别:
Temporal Trends in Food Sensitization in U.S. Children
美国儿童食物过敏的时间趋势
- 批准号:
8564924 - 财政年份:2013
- 资助金额:
$ 67.6万 - 项目类别:
Development of a Dissolving Film for Allergen Immunotherapy in Children
开发用于儿童过敏原免疫治疗的溶解膜
- 批准号:
8676849 - 财政年份:2013
- 资助金额:
$ 67.6万 - 项目类别:
Development of a Dissolving Film for Allergen Immunotherapy in Children
开发用于儿童过敏原免疫治疗的溶解膜
- 批准号:
8510886 - 财政年份:2013
- 资助金额:
$ 67.6万 - 项目类别:
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