Training Program in Cardiac Innovation

项目摘要 美国人口中的心血管疾病一直是衰弱和死亡的主要来源。 尽管有更多的预防、诊断和治疗选择。这种情况要求增加科学研究 理解并创新地将这些发现应用于患者的护理，以预防或治疗心脏 疾病。这一心血管创新培训计划旨在教授科学和技术技能 有必要发展一个新的想法，并将这个想法贯彻到人类的概念证明中。培训计划 利用明尼苏达大学利乐黑心脏研究所的独特优势 明尼苏达大学更广泛的转化医学和企业家社区，以及 双子城的生物科技、制药和设备行业。该应用程序将培训基础和临床科学家 一个跨学科的环境，目标是为他们提供洞察力和工具，使他们能够成功地 从构思到在人身上实现的想法。因此，这一新培训计划的主要目标是 提供一个跨学科的研究和培训环境，学员将在其中接触到连续的 从概念概念到基础、小动物、大动物和人类的技术发展 级别。学员将受益于社区在基础、翻译和临床科学、培训方面的优势。 在心血管创新和创业，以及行业互动和指导方面。有几个 该培训计划的独特之处：1)注重心血管科学，2)其科学资质 培训师，3)专注于创新的课程，4)行业导师的存在，以及5)机会 有意义的行业互动。该计划将由基础心血管课程组成，并由 心血管创新方面的具体培训。每个实习生将被要求参加巴肯创新 研究员计划。该计划的目标是通过培养领导力和 医学创新的风险管理教学。学员还将参加卡尔森学院 管理医疗行业领导学院(MILI)计划。MILI为学生提供创新培训， 通过特定行业的课程和对新兴市场的独特实践评估获得知识和经验 来自全球各地的技术。学员须修读四个由 技术领导力学院：1)创新、领导力和沟通，2)如何创造和激励 创新文化，3)技术环境中的交流：发展写作和展示技能， 4)一年一度的“成为医疗技术创新者”创新工作坊。学员将参与一项 至少3年的研究培训。头两年的培训将用于创新和其他教学 以及开展这项研究的责任。第三年将主要致力于制定与此相关的业务计划 并为职业发展撰写一份适当的拨款申请。对于博士来说，这将包括 对于K99/R01奖项申请，对于MD学员，申请K08或K23课程。

Project Summary Cardiovascular disease in the American population is continuously a major source of debilitation and death despite increased prevention, diagnostic, and treatment options. This situation calls for increased scientific understanding and innovative application of these findings to the care of patients in order to prevent or cure heart disease. This training program in cardiovascular innovation is designed to teach the scientific and technical skills necessary to develop a novel idea and carry this idea through to proof of concept in man. The training program takes unique advantage of the strengths of the Lillehei Heart Institute, the University of Minnesota Cardiovascular Division, the wider community of translational medicine and entrepreneurship at the University of Minnesota, and the Twin Cities biotech, pharma, and device industries. This application will train basic and clinical scientists in an interdisciplinary environment with the goal of giving them the insight and tools to be able to successfully carry an idea from conception to implementation in man. Therefore, the major goal of this new Training Program is to provide an interdisciplinary research and training environment wherein trainees will be exposed to the continuum of technological development from conceptual idea to testing at the basic, small animal, large animal, and human levels. Trainees will be advantaged by community strengths in basic, translational, and clinical science, training in cardiovascular innovation and entrepreneurship, and industry interactions and mentorship. There are several unique features of this training program: 1) a focus on cardiovascular sciences, 2) scientific qualification of its Trainers, 3) curriculum focused on innovation, 4) presence of industry mentors, and 5) an opportunity for meaningful industry interactions. The program will consist of a basic cardiovascular curriculum augmented by specific training in cardiovascular innovation. Each trainee will be required to participate in the Bakken Innovation Fellows Program. The goal of this program is to train the next leaders in medtech by fostering leadership and teaching risk management for medical innovations. Trainees will also partake of the Carlson School of Management Medical Industry Leadership Institute (MILI) program. MILI offers students innovative training, knowledge, and experiences through industry-specific courses and unique, hands-on evaluations of emerging technologies from around the globe. Trainees will be required to take 4 relevant half-day courses offered by the Technological Leadership Institute: 1) Innovation, Leadership & Communication, 2) How to Create and Stimulate a Culture of Innovation, 3) Communication in a Technical Environment: Developing Writing and Presenting Skills, and 4) the yearly Innovation Workshop "Becoming a Medical Technology Innovator." Trainees will engage in a minimum of 3 years of research training. The first two years of training will be for innovation and other didactics and for carrying out the research. Year 3 will be dedicated predominantly to developing a business plan related to the project and writing an appropriate grant application for career advancement. For PhDs, this would consist of a K99/R01 award application, and for MD trainees, the application would be for the K08 or K23 programs.