Center for Visual and Neurocognitive Rehabilitation

视觉和神经认知康复中心

• 批准号: 10268983
• 负责人: A. M. Barrett
• 金额: --
• 依托单位: VETERANS HEALTH ADMINISTRATION
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-10-01 至 2023-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10268983
• 关键词: Age related macular degeneration; Aging; Alzheimer' s Disease; Animal Model; Animals; Biomedical Engineering; Brain Diseases; Caring; Clinical Trials; Communities; Disease; Doctor of Philosophy; Ensure; Extramural Activities; Fostering; Funding; Goals; Grant; Health; Human; Institutes; Intervention; Joints; Literature; Mentorship; Mission; Molecular Biology; Neural Retina; Neurocognitive; Neurocognitive Deficit; Neurology; Ophthalmology; Patients; Personal Satisfaction; Physical Exercise; Physical Medicine; Recovery of Function; Rehabilitation therapy; Research; Research Personnel; Retinal Degeneration; Scientist; Services; Sleep; Stroke; System; Technology; Testing; Time; Training; Universities; Veterans; Visual; Visual impairment; Wolves; base; career development; design; experience; healthy aging; imaging facilities; meetings; military veteran; neural repair; neuroimaging; outreach; preclinical study; prevent; programs; psychoeducational; recruit; rehabilitation research; rehabilitation strategy; repetitive transcranial magnetic stimulation; research and development; research study; synergism; telerehabilitation

The mission of the Atlanta VAMC Rehabilitation Research and Development Center for Visual and Neurocognitive Rehabilitation (CVNR) is to foster the best possible health and well-being of Veterans through uniquely synergistic research studies targeting disorders impacting visual and/or neurocognitive function. Our Center's organization is designed to catalyze synergies amongst collaborating CVNR researchers and with scientist and clinician affiliates to maximize and accelerate tangible benefits for Veterans' health. The Internal Steering Group is the hub of CVNR operational decisions and comprises Krish Sathian, MD, PhD (Executive Director); Bruce Crosson, PhD (Executive Associate Director); Machelle Pardue, PhD (Associate Director for Scientific Projects); Steven Wolf, PT, PhD (Associate Director for Training), Patricia Griffiths, PhD (Assistant Director for Outreach); Keith McGregor, PhD (Career Development Awardees' Representative); and Lisa Calas (Administrative Officer). The CVNR has three Research Programs: (A) Retinal & Neural Repair, (B) Visual Rehabilitation, and (C) Neurocognitive Rehabilitation. The CVNR's emphasis is on highly collaborative research efforts that straddle and integrate across the Programs. To this end, we plan three Integrative Projects that each draw on expertise and ideas from multiple Programs: (1) Physical exercise to prevent progression of age-related macular degeneration in Veterans; (2) Repetitive transcranial magnetic stimulation in aging and stroke: mechanistic pre-clinical studies using animal models; and (3) Making a psycho-educational tele- rehabilitative sleep intervention accessible for Veterans with visual impairment and their cohabitating care- partners. Each of these projects will be funded by the CVNR for an initial 2-year period, with the goal of seeding extramurally funded research by that time. In subsequent years, additional Integrative Projects will be funded after competitive review. Note that the activity of CVNR investigators is not limited to these Integrative Projects; each investigator is involved in multiple other projects that will be further enriched by the experiences and results of the Integrative Projects. The CVNR will also fund a set of Cores to provide services to investigators. Three of these are ongoing: a Neuroimaging Core directed by Dr. Crosson, a Molecular Biology Core directed by Dr. Boatright, and an Administrative Core directed by Ms. Calas. Two additional Cores will be added in year 3 of the new grant cycle: a Physical Exercise Core directed by Dr. Nocera and a Tele-rehabilitation Core co-directed by Drs. Griffiths and McGregor and Mr. Ross. The CVNR has strong ties with local affiliates, including the Birmingham-Atlanta GRECC; Emory University, particularly its imaging centers, its Alzheimer's Disease Research Center, and its Departments of Neurology, Ophthalmology and Rehabilitation Medicine; Georgia Institute of Technology; the joint Biomedical Engineering Department of Emory and Georgia Tech; and Georgia State University. Our research findings will be shared through the national network of Centers, disseminated in the scientific literature and at scientific meetings, presented to VA and other clinicians locally and nationally, and distilled into educational programs for Veterans, other consumer groups, and the community. The CVNR is committed to capacity building by recruiting trainees as well as junior and senior investigators into the VA system and providing trainees with outstanding mentorship to ensure the continued vitality of rehabilitation research.

亚特兰大VAMC视觉和心理康复研究与发展中心的使命 神经认知康复(CVNR)是为了促进退伍军人尽可能的健康和福祉 通过针对影响视觉和/或神经认知的障碍的独特协同研究 功能。我们中心的组织旨在促进CVNR之间的协作 研究人员以及科学家和临床医生附属机构，以最大限度地提高和加速 退伍军人健康。内部指导小组是CVNR业务决策的中心，包括 Krish Sathian，医学博士，博士(执行董事)；Bruce Crosson，博士(执行副主任)；Machelle 帕杜，博士(科学项目副主任)；Steven Wolf，PT，博士(科学项目副主任) 培训)，Patricia Griffiths博士(外联助理主任)；Keith McGregor博士(职业生涯 发展奖获得者代表)和Lisa Calas(行政干事)。 CVNR有三个研究项目：(A)视网膜和神经修复，(B)视觉康复， 和(C)神经认知康复。CVNR的重点是高度合作的研究努力， 跨项目、跨项目整合。为此，我们计划三个综合项目，每个项目都 来自多个项目的专业知识和想法：(1)防止年龄相关性疾病进展的体育锻炼 退伍军人的黄斑变性；(2)老化和中风的重复经颅磁刺激： 利用动物模型进行机械性临床前研究；以及(3)制作心理教育电视节目。 视力障碍退伍军人及其同居护理可获得的康复睡眠干预- 合伙人。这些项目中的每一个都将在最初的两年内由国家志愿服务中心提供资金，目标是 到那时，正在进行外部资助的研究。在接下来的几年里，更多的综合项目将 在竞争性审查后获得资金。请注意，CVNR调查人员的活动并不限于这些 综合项目；每个调查员都参与了多个其他项目，这些项目将进一步丰富 综合项目的经验和成果。 CVNR还将为一系列核心提供资金，为调查人员提供服务。其中有三个是 正在进行：克罗森博士指导的神经成像核心，博特赖特博士指导的分子生物学核心， 和一个由卡拉斯女士指导的行政核心。将在新的第3年中添加两个额外的核心 格兰特周期：诺塞拉博士指导的体育锻炼核心和远程康复核心 格里菲斯医生和麦格雷戈先生还有罗斯先生。CVNR与当地分支机构有着密切的联系，包括 伯明翰-亚特兰大GRECC；埃默里大学，特别是它的成像中心，它的阿尔茨海默氏症 乔治亚州研究中心及其神经科、眼科和康复医学系 理工学院；埃默里和佐治亚理工学院联合生物医学工程系；以及 佐治亚州立大学。 我们的研究成果将通过全国中心网络共享，并在 在科学文献和科学会议上，提交给退伍军人事务部和其他临床医生，地方和国家， 并提炼成针对退伍军人、其他消费者群体和社区的教育项目。这个 CVNR致力于通过招募受训人员以及初级和高级调查人员进行能力建设。 加入退伍军人制度，并为学员提供出色的指导，以确保 康复研究。