Biostatistics, Epidemiology, and Research Design Core
生物统计学、流行病学和研究设计核心
基本信息
- 批准号:10218192
- 负责人:
- 金额:$ 64.83万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2013
- 资助国家:美国
- 起止时间:2013-09-01 至 2023-06-30
- 项目状态:已结题
- 来源:
- 关键词:AddressAdoptionAmerican IndiansApplications GrantsAreaBasic ScienceBiometryBiostatistical MethodsClinicalClinical ResearchClinical SciencesCommunitiesCommunity HealthComputerized Medical RecordConsultConsultationsDataData CollectionData ReportingData SetData SourcesDatabasesDegree programDevelopmentDiagnostic ProcedureDisciplineDiseaseDissemination and ImplementationEducational workshopEffectivenessEnsureEpidemiologic MethodsEpidemiologic Research DesignEpidemiologyExtramural ActivitiesFacultyFundingGrantHealthHealth ProfessionalHealth systemInfrastructureInstitutionLaboratory ResearchMaster of ScienceMeasurementMedicalMethodologyMethodsMissionOklahomaPatientsPeer ReviewPersonal SatisfactionPopulationPopulation SurveillancePrevention strategyProcessProductivityPublicationsQualitative ResearchQuality ControlRandomized Controlled Clinical TrialsRecommendationRegistriesReportingReproducibilityResearchResearch DesignResearch InfrastructureResearch MethodologyResearch PersonnelResearch Project GrantsResearch SupportResourcesRisk FactorsSample SizeScienceSecureSourceStatistical MethodsStudentsSurveysSystemTherapeutic InterventionTrainingTranslational ResearchTribesWorkanalytical methodbaseclinical careclinical data warehousecohortcommunity based researchdata qualitydata repositorydata warehousedesignepidemiology studyhealth assessmenthealth organizationimplementation designimplementation studyimprovedinnovationinstrumentintervention programlecturesmembernovelnovel strategiespopulation healthpreclinical studyprogramsresearch studysecondary analysisskillssuccesssurveillance datatranslational studytreatment strategy
项目摘要
Effective clinical and translational research requires rigorous study designs, appropriate application of analytic
methods, and careful reporting. The Biostatistics, Epidemiology, and Research Design (BERD) has been
instrumental in expanding clinical and translational research of new investigators, community partners, and
programs of the OSCTR, supporting over 470 research projects, resulting in 72 peer-reviewed publications and
112 grant applications (78 extramural and 34 intramural applications). The BERD has enhanced research
methods training (130 seminars/lectures, supporting 25 MS in Clinical and Translational Science thesis
projects), expanded the use of novel analytic methods and research designs (31 publications, 48 seminars,
five workshops, and two grant-funded projects), and expanded research infrastructure through the deployment
of a survey calling center and enhanced REDCap infrastructure, growing use from 6 projects/year to 207
projects in 2016. The revised mission of the BERD Core is to enable OSCTR investigators and partner
institutions to design, perform, and report rigorous, reproducible, and innovative studies that can be applied to
improve clinical care and patient well-being in Oklahoma and other IDeA states. To do this, the BERD Core
provides consultative expertise in biostatistics, epidemiology, and qualitative research methods (Aim 1);
coordinates a new, unique and robust data repository infrastructure and analytic skill set for clinical
epidemiologic studies (Aim 2); and develops and applies novel research designs and analytic methods focused
on the needs of OSCTR research (Aim 3). BERD Core members collaborate with investigators to address
sources of bias, identify sufficient sample sizes, select measurement instruments, perform data quality control,
manage and analyze data, and report study results. The BERD Core works with the Professional Development
Core to develop workshops on research methods, and with the Administrative Core to produce training videos,
templates, and fact sheets for the portal. A new BERD initiative with this renewal, the Clinical Data Warehouse,
leverages a unique resource developed at OUHSC to make de-identified electronic medical records available
for research to enhance the capacity for clinical epidemiologic and population health research in Oklahoma.
The BERD Core helps investigators identify appropriate data sources and variables to address their research
questions, then uses the Clinical Data Warehouse validated process to generate a project dataset. Finally, to
advance biostatistics and epidemiologic methods, the BERD Core holds monthly seminars to disseminate
novel research designs, analysis methods, and research findings. The BERD Core performs methodological
research to adapt existing methods or develop new approaches to address research questions, for example,
developing new statistical methods to reduce bias and increase estimation efficiency in small populations, such
as American Indian tribes. Together, these activities of the BERD Core enable OSCTR investigators to perform
rigorous, reproducible, and innovative research to better understand and address health needs in Oklahoma.
有效的临床和转化研究需要严格的研究设计、适当的分析应用
方法,并认真报告。生物统计学、流行病学和研究设计 (BERD)
有助于扩大新研究者、社区合作伙伴的临床和转化研究
OSCTR 计划,支持 470 多个研究项目,产生了 72 份同行评审出版物和
112 份拨款申请(78 份校外申请和 34 份校内申请)。 BERD加强了研究
方法培训(130 场研讨会/讲座,支持 25 篇临床和转化科学硕士论文
项目),扩大了新颖分析方法和研究设计的使用(31 篇出版物、48 场研讨会、
五个讲习班和两个赠款资助的项目),并通过部署扩大了研究基础设施
调查呼叫中心和增强的 REDCap 基础设施,使用量从每年 6 个项目增加到 207 个
2016 年的项目。BERD 核心的修订使命是使 OSCTR 调查人员和合作伙伴能够
机构设计、执行和报告严格的、可重复的和创新的研究,可应用于
改善俄克拉荷马州和其他 IDeA 州的临床护理和患者福祉。为此,BERD 核心
提供生物统计学、流行病学和定性研究方法方面的咨询专业知识(目标 1);
协调新的、独特的和强大的临床数据存储库基础设施和分析技能集
流行病学研究(目标 2);并开发和应用新颖的研究设计和分析方法
满足 OSCTR 研究的需求(目标 3)。 BERD 核心成员与调查人员合作解决
偏差来源,确定足够的样本量,选择测量仪器,执行数据质量控制,
管理和分析数据,并报告研究结果。 BERD 核心与专业发展部门合作
核心开发研究方法研讨会,并与行政核心一起制作培训视频,
门户的模板和情况说明书。此次更新后,BERD 推出了一项新举措:临床数据仓库,
利用 OUHSC 开发的独特资源提供去识别化的电子病历
用于提高俄克拉荷马州临床流行病学和人口健康研究能力的研究。
BERD Core 帮助研究人员确定适当的数据源和变量来开展研究
问题,然后使用临床数据仓库验证流程生成项目数据集。最后,为了
为了推进生物统计学和流行病学方法,BERD 核心每月举办研讨会来传播
新颖的研究设计、分析方法和研究结果。 BERD 核心执行方法论
研究以适应现有方法或开发新方法来解决研究问题,例如,
开发新的统计方法来减少小群体的偏差并提高估计效率,例如
作为美洲印第安部落。总之,BERD 核心的这些活动使 OSCTR 调查人员能够执行
严格、可重复和创新的研究,以更好地了解和满足俄克拉荷马州的健康需求。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Julie A Stoner其他文献
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{{ truncateString('Julie A Stoner', 18)}}的其他基金
Biostatistics, Epidemiology, and Research Design Core
生物统计学、流行病学和研究设计核心
- 批准号:
10438751 - 财政年份:2013
- 资助金额:
$ 64.83万 - 项目类别:
CVD in American Indians Study and Data Management Center and OK Field Center
美洲印第安人的CVD研究和数据管理中心和OK现场中心
- 批准号:
9274844 - 财政年份:2013
- 资助金额:
$ 64.83万 - 项目类别:
CVD in American Indians Study and Data Management Center and OK Field Center
美洲印第安人的CVD研究和数据管理中心和OK现场中心
- 批准号:
9065734 - 财政年份:2013
- 资助金额:
$ 64.83万 - 项目类别:
Examining multilevel associations in dental research
检查牙科研究中的多级关联
- 批准号:
8096690 - 财政年份:2010
- 资助金额:
$ 64.83万 - 项目类别:
Examining multilevel associations in dental research
检查牙科研究中的多级关联
- 批准号:
7989240 - 财政年份:2010
- 资助金额:
$ 64.83万 - 项目类别:
Biostatistics, Epidemiology, and Research Design Core
生物统计学、流行病学和研究设计核心
- 批准号:
9979932 - 财政年份:
- 资助金额:
$ 64.83万 - 项目类别:
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