Antibacterial wound dressings activated with tuned nanocomposites through the electrophoretic deposition techniques

通过电泳沉积技术用调谐纳米复合材料激活抗菌伤口敷料

• 批准号: 10042853
• 金额: $ 6.14万
• 依托单位: SHIMYATECH LIMITED
• 依托单位国家: 英国
• 项目类别: Grant for R&D
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=10042853
• 关键词: Antibacterial; wound; dressings; activated; tuned

ShimyaTech (ST) has developed an innovative technology for the attachment of nanofilms on solid supports for medical usage to combat the growing impact of bacterial biofilms and wound infections. With the reported sharp increases in the demand for wound care dressing products, anticipated to further extend due to the increased figures of varied incidents (from road to caesarean procedures, etc.), the innovation will offer a new generation of safer and more cost-efficient products which will induce investment, economic growth and vast benefits to public health and its costs.Our technology, built on the application of tuned nanomaterial composites attached to solid surfaces, has proven strong features to use as coating on medical devices including wound dressings. This will be a major step in prevention of the spread of infection, which incurs major costs to NHS up to £1bn per year. We have overcome key challenges in applying nanoparticles including prevention of the escape of nanoparticles and their release to the environment, which can have a detrimental effect on patient health.In this project, we aim to demonstrate the efficacy and scalability of our developed technology application in wound dressing products, and also how we can take it to markets. Some critical steps are required to take at a fast pace to prepare the technology for commercialisation and introduction to markets. We will pursue the project by forming a strong consortium to lead the scaling up of the technology and launch industrial application at wound dressing manufacturing firms. Study of market requirements and regulations for commercialisation of the technology and the prototyped wound dressings will be investigated. Public awareness and educational contents will be produced and disseminated as outcomes from the project.

ShimyaTech（ST）开发了一种创新技术，用于将纳米膜附着在医疗用途的固体载体上，以对抗细菌生物膜和伤口感染日益增长的影响。据报道，由于各种事故（从公路事故到剖腹产手术等）的数量增加，预计对伤口护理敷料产品的需求将进一步增加，这项创新将提供新一代更安全、更具成本效益的产品，这将促进投资、经济增长，并为公共卫生及其成本带来巨大利益。我们的技术建立在将经调整的纳米复合材料附着在固体表面的应用基础上，已被证明具有强大的功能，可用作医疗器械（包括伤口敷料）的涂层。这将是防止感染传播的重要一步，这将给NHS带来每年高达10亿英镑的重大成本。我们已经克服了应用纳米颗粒的关键挑战，包括防止纳米颗粒逃逸和释放到环境中，这可能对患者健康产生不利影响。在这个项目中，我们的目标是展示我们开发的技术应用在伤口敷料产品中的有效性和可扩展性，以及我们如何将其推向市场。需要快速采取一些关键步骤，为技术的商业化和推向市场做好准备。我们将通过组建一个强大的联盟来推进该项目，以领导该技术的规模化，并在伤口敷料制造公司中开展工业应用。将对该技术和原型伤口敷料商业化的市场需求和法规进行研究。作为该项目的成果，将制作和传播提高公众认识和教育的内容。