the Integrative and Multidisciplinary Pain and Aging Research Training (IMPART) Program

摘要 慢性疼痛是一个主要的公共卫生问题，衰老会增加慢性疼痛的风险， 一半的老年人报告持续性或复发性疼痛，年龄增长与更大的疼痛相关损失有关 生理和心理社会功能。目前关于疼痛和衰老的知识令人惊讶地有限，而且 该领域未来的进展取决于是否有训练有素的科学家，他们对 研究衰老和疼痛的临床前和临床研究方法。为了解决这一未得到满足的需求， 我们开发了一个新的博士后培训计划：综合和多学科的疼痛和衰老 研究培训(传授)计划，我们建议通过这次竞争来扩展和扩大这一计划 更新。传授计划的总体目标是培养优秀的独立调查人员 维持富有成效的临床和转译研究事业，解决生物-心理-社会机制 疼痛体验和/或设计临床干预措施以改善疼痛的潜在年龄相关变化 老年人的急性和慢性疼痛。为了实现这一总体目标，这一行动的具体目标 新的关于疼痛和衰老研究的博士后培训计划将：1)招募和培养有前途的初级人才 研究人员在疼痛和衰老方面进行基于机械和临床相关的翻译研究； 2)实施综合授课和体验式培训计划，为学员提供新的 研究技能以及应用这些技能来解决重要和未回答问题的知识和专业知识 关于疼痛和衰老的问题；以及3)创造一种卓越的研究文化，以确保 学员渴望高标准的科学诚信和质量，这将为他们的未来定下基调 从事疼痛和衰老研究的职业。IMPER利用两个优秀的协作研究计划， 佛罗里达大学-以老龄化研究所(IOA)为代表的老龄化研究社区，以及 疼痛研究社区，由卓越疼痛研究和干预中心(PRICE)组织。 我们非常成功地招募和培训了一批优秀和多样化的实习生 最初的筹资周期。培训教师中的每一位成员都在这两项研究中拥有出色的记录。 资金和指导经验。拟议的计划要求为6名博士后实习生提供支持 不同的培训背景，每个人都将与他们的多学科指导团队合作创建 并实施量身定做的独立发展计划，作为其培训的蓝图。实习生将实现 通过教学、研究和专业相结合的方式实现研究和职业发展目标 发展活动和计划评估将是持续的和多模式的。传授计划是 致力于促进学员的多样性，该计划将提供一种培训体验， 强调在研究诚信和道德方面的卓越表现。

Abstract Chronic pain represents a major public health concern, and aging confers increased risk for chronic pain, with half of older adults reporting persistent or recurring pain, and aging is associated with greater pain-related loss of physical and psychosocial function. Current knowledge regarding pain and aging is surprisingly limited, and future progress in the field hinges on the availability of well-trained scientists who have an appreciation for preclinical and clinical research approaches to the study of both aging and pain. To address this unmet need, we developed a new postdoctoral training program: the Integrative and Multidisciplinary Pain and Aging Research Training (IMPART) Program, and we propose to extend and expand this program via this competing renewal. The overall goal of the IMPART program is to develop outstanding independent investigators capable of sustaining productive clinical and translational research careers addressing the biopsychosocial mechanisms underlying age-related changes in the experience of pain and/or designing clinical interventions to ameliorate acute and chronic pain among older adults. In order to accomplish this overarching goal, the specific aims of this new postdoctoral training program in pain and aging research are to: 1) Recruit and train promising junior investigators to conduct mechanistically-based and clinically relevant translational research in pain and aging; 2) Implement an integrated didactic and experiential training program, which will equip trainees with new research skills and the knowledge and expertise to apply these skills to address important and unanswered questions regarding pain and aging; and 3) Create a culture of research excellence in order to ensure that trainees aspire to the high standards of scientific integrity and quality, which will set the tone for their future careers in pain and aging research. IMPART leverages two excellent and collaborative research programs at the University of Florida – the aging research community represented by the Institute on Aging (IOA), and the pain research community, organized under the Pain Research and Intervention Center of Excellence (PRICE). We have been highly successful in recruiting and training an outstanding and diverse group of trainees during the initial funding cycle. Each member of the training faculty boasts an excellent track record of both research funding and mentoring experience. The proposed program requests support for six postdoctoral trainees from a variety of training backgrounds, each of whom will work with their multidisciplinary mentoring team to create and implement a tailored independent development plan as the blueprint for their training. Trainees will achieve their research and career development objectives through a combination of didactic, research, and professional development activities, and program evaluation will be ongoing and multimodal. The IMPART Program is committed to promoting diversity among our trainees, and the program will provide a training experience that emphasizes excellence in research integrity and ethics.