Interdisciplinary Research Training in Pain and Substance Use Disorders

描述（由申请人提供）：美国疼痛问题的严重程度令人震惊。超过1亿的美国人有持续数周甚至数年的疼痛。根据医学研究所（IOM）最近的报告《缓解美国疼痛》，这种流行病每年造成的经济损失超过5000亿美元。同样，与药物滥用障碍（SUDs）相关的个人和社会成本巨大。当代神经生物学、心理学和流行病学研究已经表明疼痛和sud之间有明确的交叉关系。IOM委员会提出了两项改善国家层面研究的建议：(1)增加对疼痛跨学科研究的支持；(2)增加对疼痛研究人员的培训。在本提案中，我们描述了一个合作的博士后（博士，医学博士/博士和医学博士），跨学科的培训计划，将培养在疼痛和sud研究方面具有严格基础的科学家。18名有成就的教师都致力于跨学科合作，他们拥有从细胞到社会的互补专业知识。培训计划包括必修和选修课程、指导研究经验、个人综合研究项目、研讨会和专业发展技能的接触，包括拨款申请和手稿写作。斯坦福大学医学院麻醉学系疼痛医学部的培训项目旨在培养博士后学员的技能，使他们成为疼痛、SUD及其交叉领域的独立研究者。该培训计划将由肖恩·麦基博士领导，并与一个由资深成功科学家组成的指导委员会合作。他们将监督该计划的培训、科学和管理方面，包括严格的内部和外部评估过程。总之，这个培训项目将为斯坦福大学带来一批才华横溢的博士后学员、一支多才多艺的跨学科导师团队、一个有效的管理结构和一个世界一流的研究环境。人才和环境的结合将培养下一代研究人员，他们将推进我们对疼痛和物质使用障碍的科学知识和实践。

DESCRIPTION (provided by applicant): The magnitude of the problem of pain in the US is astounding. More than 100 million Americans have pain that persists for weeks to years. The financial toll of this epidemic cost over $500 billion per year according to the Institute of Medicine's (IOM) recent report, Relieving Pain in America. Similarly, there is a tremendous personal and society cost associated with substance abuse disorders (SUDs). Contemporary neurobiologic, psychological, and epidemiologic research has shown a clear intersection of pain and SUDs. Two of the IOM committee's recommendations for improving research at a national level are (1) increase support for interdisciplinary research in pain, and (2) increase the trainin of pain researchers. In this proposal, we describe a collaborative, postdoctoral (PhD, MD/PhD and MD), interdisciplinary, training program that will produce scientists with rigorous grounding in pain and SUDs research. The 18 accomplished faculty are all committed to interdisciplinary collaboration, which possess complementary expertise that ranges from cells-to- society. The training program includes both required and elective coursework, mentored research experiences, an individual integrated research project, seminars, and exposure to professional development skills, including grant proposal and manuscript writing. The training program in the Division of Pain Medicine, Department of Anesthesia, Stanford University School of Medicine, is intended to develop postdoctoral trainees' skills, so that they will become independent investigators in the fields of pain, SUD and their intersection. The training program will be led b Dr. Sean Mackey, in collaboration with a steering committee comprised of senior and successful scientists. They will oversee the training, scientific, and administrative aspects of the program, including a rigorous process of internal and external evaluation. In summary, this training program will bring together a talented group of post-doctoral trainees, an accomplished team of interdisciplinary mentors, an effective administrative structure, and a world-class research environment at Stanford University. The combination of talent and environment will launch the next generation of researchers who will advance our scientific knowledge and practice of pain and substance use disorders.