Integrative and Multidisciplinary Pain and Aging Research Training

综合性多学科疼痛和衰老研究培训

• 批准号: 9305825
• 负责人: Roger B Fillingim
• 金额: $ 26.58万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-01 至 2020-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9305825
• 关键词: Aging; Pain; Research Training; multidisciplinary

 DESCRIPTION (provided by applicant): As detailed in a recent Institute of Medicine (IOM) report, chronic pain represents a major public health concern, affecting 100 million U.S. adults and costing more than $500 billion annually. Aging confers increased risk for chronic pain, with half of older adults reporting persistent or recurring pain, and aging is associated with greater pain-related loss of physical and psychosocial function. Current knowledge regarding pain and aging is surprisingly limited, and future progress in the field hinges on the availability of well-trained scientists who have an appreciation for preclinical and clinical research approaches to the study of both aging and pain. At present, there are no existing NIH-funded T32 programs devoted to training in pain and aging. To address this unmet need, we propose to develop a new postdoctoral training program: the Integrative and Multidisciplinary Pain and Aging Research Training (IMPART) Program. The overall goal of the IMPART program is to develop outstanding independent investigators capable of sustaining productive clinical and translational research careers addressing the biopsychosocial mechanisms underlying age-related changes in the experience of pain and/or designing clinical interventions to ameliorate acute and chronic pain among older adults. In order to accomplish this overarching goal, the specific aims of this new postdoctoral training program in pain and aging research are to: 1) Recruit and train promising junior investigators to conduct mechanistically-based and clinically relevant translational research in pain and aging; 2) Implement an integrated didactic and experiential training program, which will equip trainees with new research skills and the knowledge and expertise to apply these skills to address important and unanswered questions regarding pain and aging; and 3) Create a culture of research excellence in order to ensure that trainees aspire to the high standards of scientific integrity and quality, which will set the tone for their future careers in pain and aging research. IMPART leverages two excellent and collaborative research programs at the University of Florida - the aging research community represented by the Institute on Aging (IOA), and the pain research community, organized under the Pain Research and Intervention Center of Excellence (PRICE). Each member of the training faculty boasts an excellent track record of both research funding and mentoring experience. The proposed program requests support for four postdoctoral trainees from a variety of training backgrounds, each of whom will work with their multidisciplinary mentoring team to create and implement a tailored independent development plan as the blueprint for their training. Trainees will achieve their research and career development objectives through a combination of didactic, research, and professional development activities, and program evaluation will be ongoing and multimodal. The IMPART Program is committed to promoting diversity among our trainees, and the program will provide a training experience that emphasizes excellence in research integrity and ethics.

 描述（由申请人提供）：如最近的医学研究所（IOM）报告所述，慢性疼痛是一个主要的公共卫生问题，影响1亿美国成年人，每年花费超过5000亿美元。衰老增加了慢性疼痛的风险，一半的老年人报告持续或复发性疼痛，衰老与更大的疼痛相关的身体和心理社会功能丧失有关。目前关于疼痛和衰老的知识非常有限，该领域的未来进展取决于训练有素的科学家的可用性，他们对衰老和疼痛研究的临床前和临床研究方法表示赞赏。目前，还没有NIH资助的T32项目专门用于疼痛和衰老方面的培训。为了解决这一未满足的需求，我们建议开发一个新的博士后培训计划：综合和多学科疼痛和衰老研究培训（IMPART）计划。IMPART计划的总体目标是培养优秀的独立研究人员，能够维持富有成效的临床和转化研究事业，解决疼痛经验中与年龄相关的变化的生物心理社会机制和/或设计临床干预措施，以改善老年人的急性和慢性疼痛。为了实现这一总体目标，这个新的疼痛和衰老研究博士后培训计划的具体目标是：1）招募和培训有前途的初级研究人员进行疼痛和衰老的机械基础和临床相关的转化研究; 2）实施综合教学和体验式培训计划，这将使学员具备新的研究技能和知识和专业知识，以应用这些技能来解决有关疼痛和衰老的重要和悬而未决的问题;和3）创造卓越的研究文化，以确保学员渴望达到科学诚信和质量的高标准，这将为他们的未来定下基调 从事疼痛和衰老研究。IMPART利用了佛罗里达大学的两个优秀的合作研究项目-以老龄化研究所（IOA）为代表的老龄化研究社区，以及在疼痛研究和干预卓越中心（PRICE）下组织的疼痛研究社区。培训教师的每个成员都拥有研究资金和指导经验的良好记录。拟议的计划要求支持来自各种培训背景的四名博士后学员，每个人都将与他们的多学科指导团队合作，创建和实施量身定制的独立发展计划，作为他们培训的蓝图。学员将通过教学，研究和专业发展活动的结合实现他们的研究和职业发展目标，并计划评估将是持续和多模式的。IMPART计划致力于促进我们的学员之间的多样性，该计划将提供一个培训经验，强调卓越的研究诚信和道德。