Comorbidity Between Body Dissatisfaction and Substance Use: A Daily Diary Study of Alcohol, Nicotine Vaping, and Cigarette Use Among Young Adults

项目总结/摘要 从青春期到青年期的发展过渡的特点是， 物质使用和身体不满意（BD;阴性，对一个人的形状和体重的主观评价）。BD 预测多种不良发育结果的发生。到了成年早期，BD影响了大多数人， 尽管妇女对超重的普遍程度和关注程度更高，但妇女和男子对超重的关注程度也更高。 物质使用和BD通常是独立研究的，但问题饮酒和 青少年BD患者吸烟表明需要研究药物使用的途径， 不同的方法来预防青少年BD的药物使用。这项研究旨在捕捉 在每日时间尺度上对BD和酒精和尼古丁使用进行时间排序，测试潜在机制 将BD与酒精和尼古丁的使用联系起来，并检查调节这些的人和天的特征， 协会.这项研究解决了两个NIDA的研究重点：与性别有关的途径的差异， 物质使用和物质使用与其他健康问题之间的共病机制。本研究 将产生关于尼古丁蒸汽/电子尼古丁输送系统使用的丰富数据，这是最近出现的一种新的尼古丁输送系统。 青年人重大公共卫生问题。目的1是调查性状BD和每周 酒精和尼古丁的使用以及缓和这些联系的个人水平特征。目标2：调查 每日BD与同一天和第二天酒精和尼古丁使用之间的人内前瞻性联系， 水平的特点，缓和这些联系。目标3是检查日常负面情绪和体重控制 动机作为每日BD与同一天和第二天酒精和尼古丁之间的人内联系的中介 分别使用。为了实现这些目标，申请人将进行为期14天的每日日记研究的125所大学 学生，产生多达1 750个每日观察和125个基线调查。分析方法将包括 回归分析（目标1）、多水平模型（目标2）和多水平结构方程模型（目标3）。 这项研究将促进对BD与酒精和尼古丁使用的共同发生的科学知识， 青年人和为弱势群体制定实时干预措施提供信息。申请人的 杰出的导师团队拥有统计分析和密集纵向方法方面的专业知识（Stephanie 兰扎），青年成人发展，性别和性别健康差距（苏珊麦克海尔），物质使用 和实施每日日记研究（格雷戈里Fosco），和BD（艾莉森场），并将指导申请人的 发展成为一名独立的研究员。申请人寻求酒精病因学方面的培训， 尼古丁使用，BD和性别，强化纵向方法，专业发展和研究 传播和负责任地开展研究。这项培训和研究将使申请人能够 为我们理解BD和物质使用之间的共同性做出了实质性贡献， 在她的职业生涯中滥用药物的途径中存在性别差异。

PROJECT SUMMARY/ABSTRACT The developmental transition from adolescence to young adulthood is characterized by escalations in both substance use and body dissatisfaction (BD; negative, subjective evaluation of one's shape and weight). BD predicts onset of multiple adverse developmental outcomes. By young adulthood BD affects the majority of women and men, although prevalence and intensity of concern with overweight is higher among women. Substance use and BD are typically studied independently, but elevated rates of problematic drinking and cigarette use among youth with BD suggest the need for research on pathways to substance use and differential approaches to preventing substance use for young adults with BD. This study aims to capture the temporal sequencing of BD and alcohol and nicotine use on a daily time scale, test potential mechanisms linking BD to alcohol and nicotine use, and examine person and day characteristics that moderate these associations. This study addresses two NIDA research priorities: gender-related differences in pathways to substance use and mechanisms of comorbidity between substance use and other health concerns. This study will yield rich data on nicotine vaping/electronic nicotine delivery system use, which has recently emerged as a significant public health concern among youth. Aim 1 is to investigate links between trait BD and weekly alcohol and nicotine use and person-level characteristics that moderate these links. Aim 2 is to investigate within-person prospective links between daily BD and same- and next-day alcohol and nicotine use and day- level characteristics that moderate these links. Aim 3 is to examine daily negative affect and weight control motivations as mediators of within-person links between daily BD and same- and next-day alcohol and nicotine use, respectively. To achieve these aims, the applicant will conduct a 14-day daily diary study of 125 college students, yielding up to 1,750 daily observations and 125 baseline surveys. The analytic approach will include regression analyses (Aim 1), multilevel modeling (Aim 2) and multilevel structural equation modeling (Aim 3). This study will advance scientific knowledge on the co-occurrence of BD and alcohol and nicotine use among young adults and inform development of real-time interventions for a vulnerable population. The applicant's exceptional mentor team has expertise in statistical analysis and intensive longitudinal methods (Stephanie Lanza), young adult development, gender, and gendered health disparities (Susan McHale), substance use and implementation of daily diary studies (Gregory Fosco), and BD (Alison Field) and will guide the applicant's development into an independent researcher. The applicant seeks training in the etiology of alcohol and nicotine use, BD and gender, intensive longitudinal methods, professional development and research dissemination, and the responsible conduct of research. This training and research will position the applicant to make substantial contributions to our understanding of the comorbidity between BD and substance use as well as gender differences in pathways to substance misuse throughout her career.