Predictors of Speech Ability in Children with Down Syndrome

摘要 言语是人类体验的一个关键方面，通常在一种看起来像是 从出生到青春期的自动过程(第1页，NAM，2016)“和 奠定了许多相关能力的基础(例如，语言和阅读，参见美国国家医学科学院 《关于言语和语言障碍的报告，2016》)。许多患有唐氏综合症的人 (三体21，DS)努力沟通并更充分地参与人类沟通 和教育学习体验，因为他们的演讲很难听懂。这个 拟议项目的目的是测量语音清晰度的准确性和语音 20名7岁DS儿童在研究开始时的可理解性及其提出的主要预测因素；0 到12岁；11.有效的治疗，言语重铸干预(见Yoder，Camarata& Woynaroski，2016)将被用来推动语音清晰度的增长，作为一种评估手段 变化的潜在后遗症。这项综合研究将包括言语测量- 发音准确性，语音韵律，一般认知能力，接受性词汇技能，以及 口腔运动能力作为DS患者言语清晰度增长的潜在预测指标的临床分析。 我们还将测量与增长相关的超段和节律因素。这个 这项研究的结果将提供有关有助于理解的因素的重要信息 DS中的言语，随后为提炼和未来的干预提供了基础 DS儿童言语障碍的治疗研究。

ABSTRACT Speech is a critical aspect of the human experience and usually develops in a “seemingly automatic process that continues from birth through adolescence (p.1, NAM, 2016)” and underlies many related abilities (e.g., language and reading, see National Academy of Medicine Report on Speech and Language Disorders, 2016). Many individuals with Down Syndrome (Trisomy 21, DS) struggle to communicate and participate more fully in human communication and educational learning experiences because their speech is difficult to understand. The purpose of the proposed project is to measure speech-articulation accuracy and speech intelligibility, and their proposed primary predictors at study entry in 20 children with DS age 7;0 to 12;11. A validated treatment, speech recast intervention (see Yoder, Camarata & Woynaroski, 2016) will be used to drive growth in speech intelligibility as a means of evaluating changes in potential sequelae of change. This integrated study will include measures of speech- articulation accuracy, speech-prosody, general cognitive ability, receptive vocabulary skills, and clinical assay of oral-motor ability as potential predictors of speech intelligibility growth in DS. We will also be measuring suprasegmental and rhythmic factors associated with growth. The results of this study will provide important information on factors that contribute to intelligible speech in DS and subsequently provide the basis for refining and future intervention investigations of treatment for speech deficits in children with DS.