Predictors of Speech Ability in Children with Down Syndrome

唐氏综合症儿童言语能力的预测因素

• 批准号: 10584659
• 负责人: Stephen Mark Camarata
• 金额: $ 15.15万
• 依托单位: VANDERBILT UNIVERSITY MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10584659
• 关键词: Academy; Accent; Accounting; Acoustics; Adolescence; Age; Articulation; Articulators; Biological Assay; Birth; Child; Clinical; Clinical Trials; Cognitive; Communication; Comprehension; Data; Development; Down Syndrome; Frequencies; Future; Goals; Growth; Human; Individual; Intervention; Intervention Studies; Investigational Therapies; Language; Language Disorders; Learning; Linguistics; Literature; Longitudinal Studies; Measures; Medicine; Modeling; Motor; Motor Skills; Outcome; Paper; Participant; Periodicity; Persons; Process; Production; Reading; Reporting; Research; Research Project Grants; School-Age Population; Series; Speech; Speech Development; Speech Disorders; Speech Intelligibility; Structure; Students; Testing; Translational Research; Variant; Vocabulary; Work; base; cognitive ability; design; experience; improved; insight; lexical; oral motor; phonology; post intervention; prospective; reading ability; skills; speech accuracy; therapy design

ABSTRACT Speech is a critical aspect of the human experience and usually develops in a “seemingly automatic process that continues from birth through adolescence (p.1, NAM, 2016)” and underlies many related abilities (e.g., language and reading, see National Academy of Medicine Report on Speech and Language Disorders, 2016). Many individuals with Down Syndrome (Trisomy 21, DS) struggle to communicate and participate more fully in human communication and educational learning experiences because their speech is difficult to understand. The purpose of the proposed project is to measure speech-articulation accuracy and speech intelligibility, and their proposed primary predictors at study entry in 20 children with DS age 7;0 to 12;11. A validated treatment, speech recast intervention (see Yoder, Camarata & Woynaroski, 2016) will be used to drive growth in speech intelligibility as a means of evaluating changes in potential sequelae of change. This integrated study will include measures of speech- articulation accuracy, speech-prosody, general cognitive ability, receptive vocabulary skills, and clinical assay of oral-motor ability as potential predictors of speech intelligibility growth in DS. We will also be measuring suprasegmental and rhythmic factors associated with growth. The results of this study will provide important information on factors that contribute to intelligible speech in DS and subsequently provide the basis for refining and future intervention investigations of treatment for speech deficits in children with DS.

摘要