Clinical and Translational Science Award
临床和转化科学奖
基本信息
- 批准号:10317650
- 负责人:
- 金额:$ 2034.35万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2015
- 资助国家:美国
- 起止时间:2015-08-18 至 2023-12-31
- 项目状态:已结题
- 来源:
- 关键词:AccelerationAddressAdoptedAgreementAwardCaringCatalogsClinical InvestigatorClinical ResearchClinical SciencesClinical TrialsClinical and Translational Science AwardsCollaborationsCommunitiesDataDevelopmentDevice or Instrument DevelopmentDisciplineDrug Delivery SystemsEffectivenessElectronic Health RecordEnsureEnvironmentEthnic groupFosteringFruitFundingGap JunctionsGood Clinical PracticeHealthHealthcare SystemsHospitalsInformaticsInfrastructureInstitutesInstitutionLicensingLifeLongevityMedicalMethodologyMethodsMissionModelingMulticenter TrialsMunicipalitiesNew YorkNew York CityOutcomePatientsPhasePopulationPopulation HeterogeneityPrivatizationProceduresProcessProviderPublicationsRaceRecording of previous eventsReproducibilityResearchResearch InstituteResearch PersonnelResearch SupportResearch TrainingResourcesSafetySchoolsScienceScientific Advances and AccomplishmentsServicesSiteSpecial PopulationSpecial Populations ResearchSpeedTechnologyTrainingTraining ProgramsTraining SupportTraining and EducationTranslatingTranslational ResearchTranslationsUnited StatesUnited States National Library of MedicineUniversitiesValidationVisionWorkforce Developmentbehavioral healthcollegecommunity organizationsdata managementdata sharingdesigndigitaldrug developmenteducation resourceselectronic dataepidemiology studyevidence basehealth care deliveryhealth differencehealth disparityhigh dimensionalityimprovedinnovationinterestmedical schoolsmembermetropolitanmultidisciplinarymultiple omicsnext generationnovelpatient orientedpopulation healthprogramsprotocol violationpublic-private partnershipracial diversityrecruitskillstraining opportunitytranslational pipelinetranslational scientistwearable device
项目摘要
Contact PD/PI: CRONSTEIN, BRUCE Neil
O. OVERALL – PROJECT SUMMARY
The translation and implementation of groundbreaking biomedical discoveries requires the dynamic coordination
of multi-disciplinary partnerships with diverse expertise, interests, and skills. The New York University (NYU)
Clinical and Translational Science Institute (CTSI) represents an innovative public–private partnership designed
to foster clinical and translational research, adopt evidence-based therapies, and apply scientific discoveries to
transform the delivery of medical care and improve health. The CTSI successfully leveraged a partnership of
institutions with unique and complementary strengths to translate science into better health, including: NYU, a
private research university with a history of public service, substantial biomedical, behavioral, and population
health expertise, and robust education and training programs; New York City Health and Hospitals (H+H), the
largest municipal healthcare system in the United States; Nathan Kline Institute (NKI), a state psychiatric institute
affiliated with NYU; and community organizations representing the richly diverse population of NYC. As the
centralized hub that coordinates and integrates activities across these partners, our CTSI catalyzes research
and facilitates access to essential core services, resources, and expertise necessary to engage in the full
spectrum of clinical and translational research across our partner institutions. We provide educational and
training opportunities for our diverse research workforce. Moreover, the CTSI serves as a nexus for collaboration
between investigators at our partner institutions and the nationwide network of CTSA hubs. We more than
doubled self-identified clinical and translational research at our hub over the past 10 years and established
collaborations between NYU, the schools and colleges of NYU, and H+H to further accelerate the pace and
impact of discovery, development, validation, and implementation across the full spectrum of translational
research. We now propose an array of innovative and evidence-based strategies within the framework of the
strategic domains enunciated by NCATS including: 1) Methods/Processes to streamline regulatory processes,
improve the efficiency, quality, and reproducibility of research and increase the rate of implementation of
research advances; 2) Collaboration/Engagement with communities, patients, providers, and researchers to
elucidate and disseminate best practices and guiding principles of team science to improve translational research
and health outcomes; 3) Informatics to provide a strong and innovative digital environment for subject
recruitment, data management, analysis, discovery, and sharing as well as access to an extensive digital
warehouse with data from electronic health records, epidemiologic studies, clinical trials, multi-omic analyses,
and biospecimens; 4) Integration Across the Lifespan with Community and Patient Stakeholders to engage
diverse NYC communities and special populations across the lifespan; and 5) Workforce Development to
advance our efforts to educate, train, and cultivate the next generation of the translational research workforce.
Project Summary/Abstract Page 302
Contact PD/PI: CRONSTEIN, BRUCE Neil
O. OVERALL –
联系 PD/PI:CRONSTEIN、BRUCE Neil
O. 总体——项目概要
突破性生物医学发现的转化和实施需要动态协调
具有不同专业知识、兴趣和技能的多学科伙伴关系。纽约大学 (NYU)
临床和转化科学研究所 (CTSI) 代表着创新的公私合作伙伴关系,旨在
促进临床和转化研究,采用循证疗法,并将科学发现应用于
改变医疗服务的提供并改善健康。 CTSI 成功地利用了以下合作伙伴关系:
具有独特和互补优势的机构,可以将科学转化为更好的健康,包括: 纽约大学,
私立研究型大学,具有公共服务历史,在生物医学、行为和人口方面具有丰富的经验
卫生专业知识以及健全的教育和培训计划;纽约市健康与医院 (H+H)
美国最大的市政医疗系统;内森·克莱恩研究所 (NKI),一所州立精神病学研究所
隶属于纽约大学;以及代表纽约市多元化人口的社区组织。作为
我们的 CTSI 是协调和整合这些合作伙伴活动的集中中心,可促进研究
并促进获得必要的核心服务、资源和专业知识,以充分参与
我们合作伙伴机构的一系列临床和转化研究。我们提供教育和
为我们多元化的研究人员提供培训机会。此外,CTSI 是合作的纽带
我们合作伙伴机构的调查人员与全国 CTSA 中心网络之间的联系。我们超过
过去 10 年来,我们中心的自我认定临床和转化研究翻了一番,并建立了
纽约大学、纽约大学各学院和 H+H 之间的合作,进一步加快步伐并
发现、开发、验证和实施对整个转化领域的影响
研究。我们现在在以下框架内提出一系列创新且基于证据的战略:
NCATS 阐述的战略领域包括: 1) 简化监管流程的方法/流程,
提高研究的效率、质量和可重复性,并提高实施率
研究进展; 2) 与社区、患者、提供者和研究人员合作/参与
阐明和传播团队科学的最佳实践和指导原则,以改进转化研究
和健康结果; 3)信息学为学科提供强大和创新的数字环境
招聘、数据管理、分析、发现和共享以及访问广泛的数字
包含来自电子健康记录、流行病学研究、临床试验、多组学分析的数据的仓库,
和生物样本; 4) 在整个生命周期中与社区和患者利益相关者进行整合
不同的纽约市社区和整个生命周期的特殊人群; 5) 劳动力发展
推进我们教育、培训和培育下一代转化研究队伍的努力。
项目摘要/摘要第 302 页
联系 PD/PI:CRONSTEIN、BRUCE Neil
O. 总体而言 –
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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BRUCE Neil CRONSTEIN其他文献
BRUCE Neil CRONSTEIN的其他文献
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{{ truncateString('BRUCE Neil CRONSTEIN', 18)}}的其他基金
Engineering Personalized Devices for Craniomaxillofacial Defects
针对颅颌面缺陷设计个性化设备
- 批准号:
10116988 - 财政年份:2019
- 资助金额:
$ 2034.35万 - 项目类别:
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