Multidisciplinary Training in Digestive Diseases

项目总结/摘要 在这份已建立（42年）、成功的多学科培训计划的更新申请中， 消化系统疾病，我们将继续培养合格的博士后个人（医学博士，和/或博士学位）学术 消化系统疾病的职业。我们的跨学科，全职教师36名科学家支持两个轨道， 潜在的受训人员：i）基础/疾病导向研究; ii）病人导向研究。基础/疾病 定向轨道仍然是一个长期存在的卓越与培训机会，在粘膜免疫学，细胞 生物学，肠道神经科学，肝脏病理生物学，以及围绕再生组织的新机会 医学/干细胞和转录/表观遗传学。这方面的培训得到以下方面的大力支持： 与美国国立卫生研究院资助的马约综合癌症中心，马约基础科学部门的互动 诊所和NIH P30消化疾病中心资助。以病人为导向的轨道，这是教育 通过马约转化科学活动中心（CTSA）的支持， 在人类遗传学/流行病学，肥胖/营养，人类成像/生理学和医疗保健科学 交付/相对有效性，后者是一个新的机构重点领域。我们继续要求 每年为通过客观和共识驱动机制选出的5名博士后学员提供支助 从每年大约100名医学博士的人才库中，博士或医学博士/博士候选人来自各种 临床和基础学科。该计划的整体成功继续是杰出的85%， 来自最近完成10年队列的受训者（n=24）进入学术医学人员 任命和资金组合，从这个队列，其中包括13个新的联邦赠款（4 K系列，5 R系列， 4架P30飞行员）。了解多样性对培训环境和成果的积极影响，我们 目前正在经历我们历史上最多样化的一章。在本报告所述期间， 受训人员为妇女，32%的任命由不同背景的申请人担任。体制 支助也继续得到有力的支持，并有详细记录。因此，这个高度建立的培训计划 保持创造性、创新性和活力，从而继续在实现其目标方面取得巨大成功。 培养个人从事胃肠病学和肝病学的学术事业。

PROJECT SUMMARY/ABSTRACT In this renewal application of an established (42 years), successful multidisciplinary training program in Digestive Diseases, we will continue to train qualified postdoctoral individuals (M.D., and/or Ph.D.) for academic careers in digestive diseases. Our interdisciplinary, full time faculty of 36 scientists supports two tracks for potential trainees: i) basic/disease oriented research; and ii) patient-oriented research. The basic/disease oriented track remains one of long-standing excellence with training opportunities in mucosal immunology, cell biology, enteric neurosciences, liver pathobiology, and new opportunities organized around regenerative medicine/stem cells and transcription/epigenetics. Training in this track is strongly supported through interactions with the NIH funded Mayo Comprehensive Cancer Center, Basic Science Departments at Mayo Clinic, and the NIH P30 Digestive Disease Center grant. The patient-oriented track, which is educationally buttressed through the Mayo Center for Translational Science Activities (CTSA), maintains training opportunities in human genetics/epidemiology, obesity/nutrition, human imaging/physiology, and the science of healthcare delivery/comparative effectiveness, the latter being a new area of institutional focus. We continue to request support for 5 postdoctoral trainees/year that are selected through objective and consensus-driven mechanisms from a talented annual pool of approximately 100 M.D., PhD, or M.D./PhD candidates derived from a variety of clinical and basic disciplines. The overall success of the program continues to be outstanding with 85% of trainees from the most recently completed 10-year cohort (n=24) entering into an academic medicine staff appointment and a funding portfolio from this cohort that includes 13 new federal grants (4 K series, 5 R series, 4 P30 pilots). Understanding the positive impact of diversity on the training environment and outcomes, we are currently experiencing our most diverse chapter in our history. Over the current reporting period 50% of the trainees are women and 32% of appointments were filled with applicants of Diverse Backgrounds. Institutional support also continues to be strong and well documented. Thus, this highly established training program remains creative, innovative, and dynamic, thereby continuing to be highly successful in achieving its goal of training individuals for academic careers in gastroenterology and hepatology.