Multidisciplinary Training in Digestive Diseases

描述（由申请人提供）：在一个既定的（38年），成功的消化系统疾病多学科培训计划的更新申请中，我们将继续培养合格的博士后个人（医学博士，和/或博士学位）消化系统疾病的学术生涯。我们的40名科学家的跨学科，全职教师支持potentil学员的两个轨道：i）基础/疾病为导向的研究;和ii）以患者为导向的研究。基本/疾病导向的道仍然是长期以来的卓越之一，在癌细胞生物学，肠道神经科学，肝脏病理学的培训机会，以及围绕再生医学/干细胞和转录/表观遗传学组织的新机会。通过与NIH资助的马约综合癌症中心、马约诊所的基础科学部门以及新获得的NIH P30消化疾病中心赠款的互动，大力支持这一方向的培训。以病人为导向的道，这是教育支持通过马约中心转化科学活动（CTSA），保持在人类遗传学/流行病学，肥胖/营养，人类成像/生理学的培训机会，并在医疗保健提供/比较有效性的科学，后者是一个新的机构重点领域的新发展轨道。上一次更新中提出的肥胖/营养倡议取得了显著成功，有3名新学员参加了这一培训。我们继续要求每年支持5名博士后学员，这些学员是通过客观和共识驱动的机制从每年约75名医学博士的人才库中选出的，博士或医学博士/博士候选人来自各种临床和基础学科。该计划的整体成功仍然是突出的，65%的学员从最近完成的10年队列（n=23）进入学术医学人员任命和资金组合从这个队列，其中包括16个新的联邦赠款（5 K系列，9 R系列，2 P30试点）。我们还继续积极招聘女性和代表性不足的少数民族候选人，在过去10年中，50%的受训人员来自女性（38%）或少数民族（12%）。机构支助也继续很强，并有详细记录。因此，这个高度建立的培训计划仍然具有创造性，创新性和动态性，从而继续在实现其培养个人在胃肠病学和肝病学学术生涯的目标方面取得了巨大成功。

DESCRIPTION (provided by applicant): In this renewal application of an established (38 years), successful multidisciplinary training program in Digestive Diseases, we will continue to train qualified postdoctoral individuals (M.D., and/or Ph.D.) for academic careers in digestive diseases. Our interdisciplinary, full time faculty of 40 scientists supports two tracks for potentil trainees: i) basic/disease oriented research; and ii) patient-oriented research. The basic/disease oriented tract remains one of long-standing excellence with training opportunities in cancer cell biology, enteric neurosciences, liver pathobiology, and new opportunities organized around regenerative medicine/stem cells and transcription/epigenetics. Training in this track is strongly supported through interactions with the NIH funded Mayo Comprehensive Cancer Center, Basic Science Departments at Mayo Clinic, and the newly acquired NIH P30 Digestive Disease Center grant. The patient-oriented tract, which is educationally buttressed through the Mayo Center for Translational Science Activities (CTSA), maintains training opportunities in human genetics/epidemiology, obesity/nutrition, human imaging/physiology, and a newly developed track in the science of healthcare delivery/comparative effectiveness, the latter being a new area of institutional focus. The initiative in obesity/nutrition proposed in the last renewal has been remarkably successful with 3 new trainees in this track. We continue to request support for 5 postdoctoral trainees/year that are selected through objective and consensus-driven mechanisms from a talented annual pool of approximately 75 M.D., PhD, or M.D./PhD candidates derived from a variety of clinical and basic disciplines. The overall success of the program continues to be outstanding with 65% of trainees from the most recently completed 10-year cohort (n=23) entering into an academic medicine staff appointment and a funding portfolio from this cohort that includes 16 new federal grants (5 K series, 9 R series, 2 P30 pilots). Our aggressive recruitment of both female and underrepresented minority candidates also continues, with 50% of the trainees from female (38%) or minority groups (12%) during the last 10 years. Institutional support also continues to be strong and well documented. Thus, this highly established training program remains creative, innovative, and dynamic, thereby continuing to be highly successful in achieving its goal of training individuals for academic careers in gastroenterology and hepatology.